FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3021167257> ?p ?o ?g. }

• W3021167257 endingPage "235" @default.
• W3021167257 startingPage "228" @default.
• W3021167257 abstract "The objectives of this study were (1) to develop a method for the determination of 10 uremic toxins (3-carboxy-4-methyl-5-propyl-2-furanpropanoic acid (CMPF), hippuric acid, indole-3-acetic acid, indoxyl sulfate, kynurenic acid, kynurenine, p-cresyl glucuronide, p-cresyl sulfate, phenylacetylglutamine and trimethylamine N-oxide (TMAO)), and 3 precursors (tyrosine, phenylalanine, tryptophan) in serum and (2) to compare two separation methods to determine the free serum fraction: rapid equilibrium dialysis (RED) and ultrafiltration (UF). The method was developed on a liquid chromatography system coupled to a tandem mass spectrometer. Fifty µL of serum sample were precipitated with methanol after addition of internal standard. The two separation methods were compared using serum samples from patients suffering from renal impairment (n = 30). The method has been validated according to the European Medicines Agency (EMA) guidelines. Calibration curves were linear from 1 to 50 ng/mL up to 10,000–50,000 ng/mL according to the compounds. The comparison between the two separation methods produced similar results for all compounds except kynurenine, tryptophan (around 30% more with UF) and indole-3-acetic acid (around 30% more with RED). This study has allowed the development and validation of a sensitive and robust assay for the quantification of free and total concentrations of 10 uremic toxins and 3 precursors in human serum." @default.
• W3021167257 created "2020-05-13" @default.
• W3021167257 creator A5018912711 @default.
• W3021167257 creator A5035072931 @default.
• W3021167257 creator A5040351790 @default.
• W3021167257 creator A5047041215 @default.
• W3021167257 creator A5054786150 @default.
• W3021167257 creator A5073978251 @default.
• W3021167257 date "2020-08-01" @default.
• W3021167257 modified "2023-10-02" @default.
• W3021167257 title "Quantification of free and protein bound uremic toxins in human serum by LC-MS/MS: Comparison of rapid equilibrium dialysis and ultrafiltration" @default.
• W3021167257 cites W1617526274 @default.
• W3021167257 cites W1977631259 @default.
• W3021167257 cites W1979920293 @default.
• W3021167257 cites W2022391402 @default.
• W3021167257 cites W2023444201 @default.
• W3021167257 cites W2030565309 @default.
• W3021167257 cites W2032788916 @default.
• W3021167257 cites W2033739825 @default.
• W3021167257 cites W2049553261 @default.
• W3021167257 cites W2062626557 @default.
• W3021167257 cites W2075905386 @default.
• W3021167257 cites W2078599166 @default.
• W3021167257 cites W2078680679 @default.
• W3021167257 cites W2094318897 @default.
• W3021167257 cites W2101431807 @default.
• W3021167257 cites W2122231873 @default.
• W3021167257 cites W2134719518 @default.
• W3021167257 cites W2139192559 @default.
• W3021167257 cites W2145073188 @default.
• W3021167257 cites W2151832866 @default.
• W3021167257 cites W2155352361 @default.
• W3021167257 cites W2162078360 @default.
• W3021167257 cites W2163494329 @default.
• W3021167257 cites W2171479422 @default.
• W3021167257 cites W224639730 @default.
• W3021167257 cites W2254482971 @default.
• W3021167257 cites W2299645303 @default.
• W3021167257 cites W2320199795 @default.
• W3021167257 cites W2468494733 @default.
• W3021167257 cites W2786999999 @default.
• W3021167257 cites W2883719276 @default.
• W3021167257 cites W2891905995 @default.
• W3021167257 cites W2902996126 @default.
• W3021167257 cites W2921978077 @default.
• W3021167257 cites W2950249245 @default.
• W3021167257 doi "https://doi.org/10.1016/j.cca.2020.04.032" @default.
• W3021167257 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32371217" @default.
• W3021167257 hasPublicationYear "2020" @default.
• W3021167257 type Work @default.
• W3021167257 sameAs 3021167257 @default.
• W3021167257 citedByCount "21" @default.
• W3021167257 countsByYear W30211672572020 @default.
• W3021167257 countsByYear W30211672572021 @default.
• W3021167257 countsByYear W30211672572022 @default.
• W3021167257 countsByYear W30211672572023 @default.
• W3021167257 crossrefType "journal-article" @default.
• W3021167257 hasAuthorship W3021167257A5018912711 @default.
• W3021167257 hasAuthorship W3021167257A5035072931 @default.
• W3021167257 hasAuthorship W3021167257A5040351790 @default.
• W3021167257 hasAuthorship W3021167257A5047041215 @default.
• W3021167257 hasAuthorship W3021167257A5054786150 @default.
• W3021167257 hasAuthorship W3021167257A5073978251 @default.
• W3021167257 hasConcept C179998833 @default.
• W3021167257 hasConcept C185592680 @default.
• W3021167257 hasConcept C2776255415 @default.
• W3021167257 hasConcept C2776673659 @default.
• W3021167257 hasConcept C2776706248 @default.
• W3021167257 hasConcept C2777431362 @default.
• W3021167257 hasConcept C2777503454 @default.
• W3021167257 hasConcept C2780026642 @default.
• W3021167257 hasConcept C2780548424 @default.
• W3021167257 hasConcept C43617362 @default.
• W3021167257 hasConcept C50817676 @default.
• W3021167257 hasConcept C515207424 @default.
• W3021167257 hasConcept C55493867 @default.
• W3021167257 hasConcept C74774607 @default.
• W3021167257 hasConceptScore W3021167257C179998833 @default.
• W3021167257 hasConceptScore W3021167257C185592680 @default.
• W3021167257 hasConceptScore W3021167257C2776255415 @default.
• W3021167257 hasConceptScore W3021167257C2776673659 @default.
• W3021167257 hasConceptScore W3021167257C2776706248 @default.
• W3021167257 hasConceptScore W3021167257C2777431362 @default.
• W3021167257 hasConceptScore W3021167257C2777503454 @default.
• W3021167257 hasConceptScore W3021167257C2780026642 @default.
• W3021167257 hasConceptScore W3021167257C2780548424 @default.
• W3021167257 hasConceptScore W3021167257C43617362 @default.
• W3021167257 hasConceptScore W3021167257C50817676 @default.
• W3021167257 hasConceptScore W3021167257C515207424 @default.
• W3021167257 hasConceptScore W3021167257C55493867 @default.
• W3021167257 hasConceptScore W3021167257C74774607 @default.
• W3021167257 hasLocation W30211672571 @default.
• W3021167257 hasLocation W30211672572 @default.
• W3021167257 hasOpenAccess W3021167257 @default.
• W3021167257 hasPrimaryLocation W30211672571 @default.
• W3021167257 hasRelatedWork W1568974491 @default.
• W3021167257 hasRelatedWork W1983807977 @default.
• W3021167257 hasRelatedWork W1987299088 @default.

• next