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- W3021227833 abstract "This chapter provides an overview of vitamin E. Vitamin E, which belongs to the fat-soluble group of vitamins, is easily absorbed from the intestine in the presence of adequate amounts of bile and pancreatic juice. It is absorbed mainly via the lymphatics, the acetate being absorbed more slowly than the free alcohol form. Once through the intestinal barrier, it is distributed throughout the tissues of the animal body, the main storage depots being the liver and adipose tissue. About 90 % of tissue tocopherol is in the α form. Distribution is uneven within the animal body. There is a remarkably high level in the pituitary. The adrenal, ovary, testes, and uterus have fairly high contents in comparison with such tissues as lung, kidney, spleen, pancreas, and muscle. Variations in tissue ε levels occur in hypercholesterolaemia and pregnancy when levels rise above normal. Levels decline following prolonged physical or mental stress, anoxia, and malnutrition. The presence of large amounts of unsaturated fatty acids in the diet or deficiency in protein, vitamins A1, B6, or the essential fatty acids, tend to deplete stores of vitamin E. The chapter explains the role of vitamin E and its deficiency. The vitamin is a potent anticoagulant, and in its absence, thrombi form readily in the blood vascular system. The cerebellar encephalomalacia noted in ε deficient chicks and also seen in the human infant appears to develop on a basis of vascular thrombosis." @default.
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- W3021227833 date "1970-01-01" @default.
- W3021227833 modified "2023-10-16" @default.
- W3021227833 title "Vitamin E" @default.
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- W3021227833 doi "https://doi.org/10.1016/b978-0-433-17320-5.50012-0" @default.
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