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- W3021230448 abstract "Publisher SummaryElectron microscope autoradiography requires the consideration of several technical factors, including not only the choice of isotope but also the choice of tissue preparation procedure, choice of photographic emulsion and its application onto the ultrathin sections, type of development, and evaluation of qualitative or quantitative results. Additionally, an evaluation must be made beforehand of the possibility of achieving high enough concentrations of the isotopes in the tissue. In other words, the experimental system has to be analyzed with respect to the possibility of obtaining results within a reasonable time, for example, using small experimental animals or in vitro systems. The technique requires several types of controls and a determination of whether some of the isotopes have been extracted during the preparatory steps or have diffused within the tissue. Water-soluble labeled substances, such as ions and many small molecules, cannot be localized in the tissues by standard procedures." @default.
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- W3021230448 date "1999-01-01" @default.
- W3021230448 modified "2023-09-27" @default.
- W3021230448 title "AUTORADIOGRAPHY" @default.
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- W3021230448 doi "https://doi.org/10.1016/b978-012480610-8/50016-0" @default.
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