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• W3021262501 abstract "Publisher SummaryThis chapter discusses menopause. The term menopause denotes the final cessation of menstruation; it is therefore difficult to diagnose except in retrospect. Six months amenorrhea at the age of 45–55 years or more is arbitrarily, but not always correctly, taken to imply that the menopause has occurred, provided that pregnancy has been excluded. The onset of the menopause is related to the depletion of graafian follicles in the ovaries. Cessation of menstruation is preceded by erratic maturation of the remaining follicles with an overall decline in estradiol levels and an increase in FSH and later in LH levels. Sometimes after several months more follicles will be stimulated to make enough estradiol to cause endometrial proliferation and a further bleeding episode. Ovulation may also occur after a gap of several months amenorrhea. The symptoms most commonly complained of around the time of the menopause are hot flushes. They are probably experienced by more than 75% of women. A typical hot flush lasts for a few seconds to several minutes and consists of reddening of the skin over the neck, face, and chest accompanied by a feeling of heat and followed by sometimes profuse perspiration. An uneasy feeling commonly occurs just before the onset of the flush." @default.
• W3021262501 created "2020-05-13" @default.
• W3021262501 creator A5007340977 @default.
• W3021262501 date "1991-01-01" @default.
• W3021262501 modified "2023-09-25" @default.
• W3021262501 title "The menopause" @default.
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• W3021262501 doi "https://doi.org/10.1016/b978-0-7506-1171-8.50018-0" @default.
• W3021262501 hasPublicationYear "1991" @default.
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