Matches in SemOpenAlex for { <https://semopenalex.org/work/W3021282625> ?p ?o ?g. }
Showing items 1 to 85 of
85
with 100 items per page.
- W3021282625 abstract "The binding of spin-labeled fatty acids (SLFAs) to the human serum albumin (HSA) examined by electron paramagnetic resonance (EPR) spectroscopy was studied to evaluate the potential of the HSA/SLFA/EPR technique as a biomarking tool for cancer. A comparative study was performed on two spin labels with nitroxide groups attached at opposite ends of the fatty acid (FA) chain, 5-doxyl stearic (5-DS) and 16-doxyl stearic (16-DS) acid. The effects of incubation time, different [SLFA]/[HSA] molar ratios, ethanol, and temperature showed that the position of the nitroxide group produces certain differences in binding between the two SLFAs. Spectra for different [SLFA]/[HSA] molar ratios were decomposed into two spectral components, which correspond to the weakly and strongly bound SLFAs. The reduction of SLFA with ascorbate showed the existence of a two component process, fast and slow, confirming the decomposition results. Warfarin has no effect on the binding of the two SLFAs, whereas ibuprofen significantly decreases the binding of 5-DS and has no effect on 16-DS. Together, the results of this study indicate that both SLFAs, 5-DS and 16-DS, should be used for the study of HSA conformational changes in blood induced by various medical conditions." @default.
- W3021282625 created "2020-05-13" @default.
- W3021282625 creator A5021881174 @default.
- W3021282625 creator A5029070051 @default.
- W3021282625 creator A5074830735 @default.
- W3021282625 creator A5077682381 @default.
- W3021282625 creator A5083873586 @default.
- W3021282625 date "2014-01-01" @default.
- W3021282625 modified "2023-09-23" @default.
- W3021282625 title "Binding of Doxyl Stearic Spin Labels to Human Serum Albumin: An EPR Study B" @default.
- W3021282625 hasPublicationYear "2014" @default.
- W3021282625 type Work @default.
- W3021282625 sameAs 3021282625 @default.
- W3021282625 citedByCount "0" @default.
- W3021282625 crossrefType "journal-article" @default.
- W3021282625 hasAuthorship W3021282625A5021881174 @default.
- W3021282625 hasAuthorship W3021282625A5029070051 @default.
- W3021282625 hasAuthorship W3021282625A5074830735 @default.
- W3021282625 hasAuthorship W3021282625A5077682381 @default.
- W3021282625 hasAuthorship W3021282625A5083873586 @default.
- W3021282625 hasConcept C111998727 @default.
- W3021282625 hasConcept C113196181 @default.
- W3021282625 hasConcept C121332964 @default.
- W3021282625 hasConcept C15920480 @default.
- W3021282625 hasConcept C165616093 @default.
- W3021282625 hasConcept C169912494 @default.
- W3021282625 hasConcept C178790620 @default.
- W3021282625 hasConcept C185592680 @default.
- W3021282625 hasConcept C187961010 @default.
- W3021282625 hasConcept C2778597219 @default.
- W3021282625 hasConcept C2779516699 @default.
- W3021282625 hasConcept C41625074 @default.
- W3021282625 hasConcept C43617362 @default.
- W3021282625 hasConcept C46141821 @default.
- W3021282625 hasConcept C521977710 @default.
- W3021282625 hasConcept C55493867 @default.
- W3021282625 hasConcept C71240020 @default.
- W3021282625 hasConcept C79123411 @default.
- W3021282625 hasConcept C8010536 @default.
- W3021282625 hasConceptScore W3021282625C111998727 @default.
- W3021282625 hasConceptScore W3021282625C113196181 @default.
- W3021282625 hasConceptScore W3021282625C121332964 @default.
- W3021282625 hasConceptScore W3021282625C15920480 @default.
- W3021282625 hasConceptScore W3021282625C165616093 @default.
- W3021282625 hasConceptScore W3021282625C169912494 @default.
- W3021282625 hasConceptScore W3021282625C178790620 @default.
- W3021282625 hasConceptScore W3021282625C185592680 @default.
- W3021282625 hasConceptScore W3021282625C187961010 @default.
- W3021282625 hasConceptScore W3021282625C2778597219 @default.
- W3021282625 hasConceptScore W3021282625C2779516699 @default.
- W3021282625 hasConceptScore W3021282625C41625074 @default.
- W3021282625 hasConceptScore W3021282625C43617362 @default.
- W3021282625 hasConceptScore W3021282625C46141821 @default.
- W3021282625 hasConceptScore W3021282625C521977710 @default.
- W3021282625 hasConceptScore W3021282625C55493867 @default.
- W3021282625 hasConceptScore W3021282625C71240020 @default.
- W3021282625 hasConceptScore W3021282625C79123411 @default.
- W3021282625 hasConceptScore W3021282625C8010536 @default.
- W3021282625 hasLocation W30212826251 @default.
- W3021282625 hasOpenAccess W3021282625 @default.
- W3021282625 hasPrimaryLocation W30212826251 @default.
- W3021282625 hasRelatedWork W1044236724 @default.
- W3021282625 hasRelatedWork W1506202992 @default.
- W3021282625 hasRelatedWork W1573311248 @default.
- W3021282625 hasRelatedWork W1911040586 @default.
- W3021282625 hasRelatedWork W1969555198 @default.
- W3021282625 hasRelatedWork W1974655475 @default.
- W3021282625 hasRelatedWork W1992962384 @default.
- W3021282625 hasRelatedWork W1999019003 @default.
- W3021282625 hasRelatedWork W2015793620 @default.
- W3021282625 hasRelatedWork W2070568701 @default.
- W3021282625 hasRelatedWork W2094167818 @default.
- W3021282625 hasRelatedWork W2209849597 @default.
- W3021282625 hasRelatedWork W2334006994 @default.
- W3021282625 hasRelatedWork W2364776518 @default.
- W3021282625 hasRelatedWork W2376147623 @default.
- W3021282625 hasRelatedWork W2531146703 @default.
- W3021282625 hasRelatedWork W2802135436 @default.
- W3021282625 hasRelatedWork W2899397308 @default.
- W3021282625 hasRelatedWork W3139440032 @default.
- W3021282625 hasRelatedWork W3143819022 @default.
- W3021282625 isParatext "false" @default.
- W3021282625 isRetracted "false" @default.
- W3021282625 magId "3021282625" @default.
- W3021282625 workType "article" @default.