FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3021327311> ?p ?o ?g. }

• W3021327311 abstract "Several cases of acquired aphasia for American Sign Language (ASL) have been described in individuals with left hemispheric lesions from stroke or trauma. Here, we present 2 patients with Alzheimer disease and congenital deafness who developed aphasia for sign language. Case 1: A 71–year old woman with congenital deafness was brought to the dementia clinic by her daughter, who reported a gradually progressive decline in memory, orientation, and activities of daily living over approximately 4 years, and apparent problems with language for 1 year. The patient often had difficulty coming up with the correct sign for objects, and had an increasing tendency to give the sign for ‘item’ for any object. Sometimes she would use inappropriate or nonsense signs and also sometimes appeared to have difficulty understanding others’ signing to her. These language difficulties were also noticed by the clinic's ASL interpreter. Neuropsychological testing revealed dementia with a prominent amnestic component and anomia; constructional praxis was intact. Routine laboratories and a head CT were normal. Her aphasia and dementia progressed over the next 4 years until her death. Case 2: An 80–year old congenitally deaf man presented with a 2–year history of gradually progressive short–term memory loss, disorientation, and mood swings. Neuropsychological testing revealed dementia with a prominent amnestic component and depressive symptoms. Routine laboratories and a head CT were unremarkable. Treatment with an antidepressant produced improvement of his mood and energy, but not cognition. Over the next year, he started having difficulty understanding both signed and written language. His wife also reported that his own signing was becoming “sparse,” whereas in the past he had had a broad vocabulary. Numerous cases of aphasia for ASL in stroke or head injury patients have been studied and described since the 1800's. Neurological, neuropsychological, and functional neuroimaging testing has demonstrated that sign language depends upon the same neuroanatomic areas as spoken language, as opposed to gestural language or praxis. Our patients exhibited the same aphasia symptoms exhibited by many hearing individuals with Alzheimer disease. To our knowledge, this is the first formal report of ASL aphasia in Alzheimer disease." @default.
• W3021327311 created "2020-05-13" @default.
• W3021327311 creator A5012811609 @default.
• W3021327311 creator A5071364728 @default.
• W3021327311 date "2006-07-01" @default.
• W3021327311 modified "2023-09-27" @default.
• W3021327311 title "P3-073: American Sign Language aphasia in Alzheimer disease" @default.
• W3021327311 doi "https://doi.org/10.1016/j.jalz.2006.05.1340" @default.
• W3021327311 hasPublicationYear "2006" @default.
• W3021327311 type Work @default.
• W3021327311 sameAs 3021327311 @default.
• W3021327311 citedByCount "1" @default.
• W3021327311 countsByYear W30213273112016 @default.
• W3021327311 crossrefType "journal-article" @default.
• W3021327311 hasAuthorship W3021327311A5012811609 @default.
• W3021327311 hasAuthorship W3021327311A5071364728 @default.
• W3021327311 hasConcept C118552586 @default.
• W3021327311 hasConcept C138885662 @default.
• W3021327311 hasConcept C14216870 @default.
• W3021327311 hasConcept C142724271 @default.
• W3021327311 hasConcept C15744967 @default.
• W3021327311 hasConcept C169900460 @default.
• W3021327311 hasConcept C2779134260 @default.
• W3021327311 hasConcept C2779422653 @default.
• W3021327311 hasConcept C2779483572 @default.
• W3021327311 hasConcept C2780733359 @default.
• W3021327311 hasConcept C41895202 @default.
• W3021327311 hasConcept C522192633 @default.
• W3021327311 hasConcept C548259974 @default.
• W3021327311 hasConcept C71924100 @default.
• W3021327311 hasConcept C94445187 @default.
• W3021327311 hasConceptScore W3021327311C118552586 @default.
• W3021327311 hasConceptScore W3021327311C138885662 @default.
• W3021327311 hasConceptScore W3021327311C14216870 @default.
• W3021327311 hasConceptScore W3021327311C142724271 @default.
• W3021327311 hasConceptScore W3021327311C15744967 @default.
• W3021327311 hasConceptScore W3021327311C169900460 @default.
• W3021327311 hasConceptScore W3021327311C2779134260 @default.
• W3021327311 hasConceptScore W3021327311C2779422653 @default.
• W3021327311 hasConceptScore W3021327311C2779483572 @default.
• W3021327311 hasConceptScore W3021327311C2780733359 @default.
• W3021327311 hasConceptScore W3021327311C41895202 @default.
• W3021327311 hasConceptScore W3021327311C522192633 @default.
• W3021327311 hasConceptScore W3021327311C548259974 @default.
• W3021327311 hasConceptScore W3021327311C71924100 @default.
• W3021327311 hasConceptScore W3021327311C94445187 @default.
• W3021327311 hasIssue "3S_Part_13" @default.
• W3021327311 hasLocation W30213273111 @default.
• W3021327311 hasOpenAccess W3021327311 @default.
• W3021327311 hasPrimaryLocation W30213273111 @default.
• W3021327311 hasRelatedWork W1840873375 @default.
• W3021327311 hasRelatedWork W1992691119 @default.
• W3021327311 hasRelatedWork W2040022214 @default.
• W3021327311 hasRelatedWork W2067922485 @default.
• W3021327311 hasRelatedWork W2107945060 @default.
• W3021327311 hasRelatedWork W2128898170 @default.
• W3021327311 hasRelatedWork W2323529116 @default.
• W3021327311 hasRelatedWork W2618582477 @default.
• W3021327311 hasRelatedWork W3032356544 @default.
• W3021327311 hasRelatedWork W565478097 @default.
• W3021327311 hasVolume "2" @default.
• W3021327311 isParatext "false" @default.
• W3021327311 isRetracted "false" @default.
• W3021327311 magId "3021327311" @default.
• W3021327311 workType "article" @default.