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Matches in SemOpenAlex for { <https://semopenalex.org/work/W3021373705> ?p ?o ?g. }

• W3021373705 abstract "We describe here the design, synthesis, and evaluation of a macrocyclic peptidomimetic as a potent agent targeting enterovirus A71 (EV71). The compound has a 15-membered macrocyclic ring in a defined conformation. Yamaguchi esterification reaction was used to close the 15-membered macrocycle instead of the typical Ru-catalyzed ring-closing olefin metathesis reaction. The crystallographic characterization of the complex between this compound and its target, 3C protease from EV71, validated the design and paved the way for the generation of a new series of anti-EV71 agents." @default.
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• W3021373705 date "2020-06-01" @default.
• W3021373705 modified "2023-10-14" @default.
• W3021373705 title "Design, synthesis, and evaluation of a novel macrocyclic anti-EV71 agent" @default.
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• W3021373705 doi "https://doi.org/10.1016/j.bmc.2020.115551" @default.
• W3021373705 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32503695" @default.
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