FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3021388182> ?p ?o ?g. }

• W3021388182 abstract "Introduction Computed Tomography Colonoscopy (CTC) is increasingly being used as an alternative to optical colonoscopy (OC). The SIGGAR trial and COCOS study have shown CTC to be an accurate and safe alternative to OC for diagnosis of colorectal cancer (CRC) and large polyps. Our aim was to compare various performance indicators between CTC and OC in the lower GI straight to test (STT) 2 week wait (2 WW) pathway. Methods The investigation of choice for the lower GI 2 WW STT cohort between Nov 2014 and Oct 2015 was OC with CTC being the first-line test between Jan 2016 and Dec 2016. We retrospectively analysed 12 months’ data for both cohorts. Outcomes included completion rate, polyp detection rate (PDR), adenoma detection rate (ADR) and CRC detection rates. Results 1135 patients attended for OC versus 1829 for CTC. Significantly more OC were cancelled on the day compared to CTC (6.5% v 2% p=0.0001). OC had a completion rate measured by caecal intubation of 86% versus 100% of CTC (p=0.0001). The diagnostic study rate measured by adequate bowel preparation/faecal tagging and distension was 89.3% at OC (adequate preparation) versus 98.4% for CTC (p=0.0001). CRC detection rate was 4.5% (95% CI 3.43% to 5.95%) in the OC group versus 4.9% (95% CI 3.97% to 5.95%) in the CTC group (p=>0.005). The PDR was significantly higher in the OC group compared to the CTC group (25.1% (95% CI 22.95% to 27.32%) v 13.5% (95% CI 11.95% to 15.11%) p=0.0001). However, 61.7% of the polyps detected at OC were ≤5 mm which are not routinely reported on CTC. PDR for polyps>5 mm at OC was 9.6% (95% CI 7.98% to 11.54%) versus 13.5% at CTC (p=0.0024). The ADR at OC was significantly higher than in the CTC (16.5% (95% CI 14.38% to 18.85%) versus 9.8% (95% CI 8.53% to 11.29%) p=0.0001). The non-CRC detection rate in the CTC group was 4.3%. Conclusions CTC and OC have comparable CRC detection rates for patients referred via the 2 WW STT lower GI pathway. However, the PDR and ADR are higher with OC, this data is skewed by the number of diminutive polyps identified at OC that are not routinely reported at CTC. Also, a number of cases with 5–10 mm polyps at CTC did not progress to OC. Long term follow up data is required to compare interval cancer detection rates in these cohorts to assess the impact of not reporting/identifying sub 5 mm polyps. From a service delivery perspective, the on the day cancellation rate, completion rate and diagnostic study rate for CTC were significantly better than OC in the STT patient. An additional benefit of CTC is the diagnosis of non-colonic cancers, the rate of which was comparable to the CRC rate." @default.
• W3021388182 created "2020-05-13" @default.
• W3021388182 creator A5001065677 @default.
• W3021388182 creator A5023785758 @default.
• W3021388182 creator A5031707629 @default.
• W3021388182 creator A5054690992 @default.
• W3021388182 creator A5061791873 @default.
• W3021388182 creator A5063642392 @default.
• W3021388182 creator A5066526602 @default.
• W3021388182 date "2018-06-01" @default.
• W3021388182 modified "2023-09-27" @default.
• W3021388182 title "PTH-021 Cancer and adenoma detection rate in 2-week wait colonoscopy and CT colonography- tertiary centre experience" @default.
• W3021388182 doi "https://doi.org/10.1136/gutjnl-2018-bsgabstracts.43" @default.
• W3021388182 hasPublicationYear "2018" @default.
• W3021388182 type Work @default.
• W3021388182 sameAs 3021388182 @default.
• W3021388182 citedByCount "0" @default.
• W3021388182 crossrefType "proceedings-article" @default.
• W3021388182 hasAuthorship W3021388182A5001065677 @default.
• W3021388182 hasAuthorship W3021388182A5023785758 @default.
• W3021388182 hasAuthorship W3021388182A5031707629 @default.
• W3021388182 hasAuthorship W3021388182A5054690992 @default.
• W3021388182 hasAuthorship W3021388182A5061791873 @default.
• W3021388182 hasAuthorship W3021388182A5063642392 @default.
• W3021388182 hasAuthorship W3021388182A5066526602 @default.
• W3021388182 hasBestOaLocation W30213881821 @default.
• W3021388182 hasConcept C121608353 @default.
• W3021388182 hasConcept C126322002 @default.
• W3021388182 hasConcept C2777428134 @default.
• W3021388182 hasConcept C2778435480 @default.
• W3021388182 hasConcept C3019222653 @default.
• W3021388182 hasConcept C526805850 @default.
• W3021388182 hasConcept C71924100 @default.
• W3021388182 hasConcept C90924648 @default.
• W3021388182 hasConceptScore W3021388182C121608353 @default.
• W3021388182 hasConceptScore W3021388182C126322002 @default.
• W3021388182 hasConceptScore W3021388182C2777428134 @default.
• W3021388182 hasConceptScore W3021388182C2778435480 @default.
• W3021388182 hasConceptScore W3021388182C3019222653 @default.
• W3021388182 hasConceptScore W3021388182C526805850 @default.
• W3021388182 hasConceptScore W3021388182C71924100 @default.
• W3021388182 hasConceptScore W3021388182C90924648 @default.
• W3021388182 hasLocation W30213881821 @default.
• W3021388182 hasOpenAccess W3021388182 @default.
• W3021388182 hasPrimaryLocation W30213881821 @default.
• W3021388182 hasRelatedWork W1933522605 @default.
• W3021388182 hasRelatedWork W1966703559 @default.
• W3021388182 hasRelatedWork W2005591302 @default.
• W3021388182 hasRelatedWork W2007309073 @default.
• W3021388182 hasRelatedWork W2019884211 @default.
• W3021388182 hasRelatedWork W2026562723 @default.
• W3021388182 hasRelatedWork W2061148304 @default.
• W3021388182 hasRelatedWork W2104232640 @default.
• W3021388182 hasRelatedWork W2118772243 @default.
• W3021388182 hasRelatedWork W2131102084 @default.
• W3021388182 hasRelatedWork W2132063653 @default.
• W3021388182 hasRelatedWork W2158045223 @default.
• W3021388182 hasRelatedWork W2321848139 @default.
• W3021388182 hasRelatedWork W2336545789 @default.
• W3021388182 hasRelatedWork W2617336358 @default.
• W3021388182 hasRelatedWork W2795112675 @default.
• W3021388182 hasRelatedWork W2891863665 @default.
• W3021388182 hasRelatedWork W2911223159 @default.
• W3021388182 hasRelatedWork W3119924552 @default.
• W3021388182 hasRelatedWork W3136077307 @default.
• W3021388182 isParatext "false" @default.
• W3021388182 isRetracted "false" @default.
• W3021388182 magId "3021388182" @default.
• W3021388182 workType "article" @default.