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- W3021400688 abstract "Introduction. Congenital toxoplasmosis represents an important cause of infant morbidity and mortality. The etiological agent is a largely spread parasite microorganism, Toxoplasma gondii. Fetal infection is possible only when the pregnant patient contracts the disease during pregnancy. The topography of fetal lesions involves especially the brain and the eyes. The most common form of the disease is represented by congenital encephalomyelitis, manifested by hydrocephalus, microcephaly, microphthalmia, typical signs of cerebellar suffering and ocular impairment. The definitive diagnosis involves the detection of specific IgM antibodies in the patient’s blood, the persistence of IgG antibodies after the age of 1 year old, or the detection by PCR of the parasite DNA in the blood and cerebrospinal fluid. Objective. The paper presents the medical evolution of a case of congenital toxoplasmosis. Materials and method. We present the case of a male baby, 12 months old, institutionalized after birth, who was diagnosed with congenital toxoplasmosis at the age of 6 months old. Results. The evolution was unfavorable, the patient developing hydrocephalus, which necessitated the mounting of a ventriculoperitoneal shunt, and frequent meningitis episodes, of both viral and bacterial etiology. Thereafter, the patient developed spastic tetraparesis, generalized epilepsy, profound mental retardation and multiple respiratory infections. Conclusions. The clinical manifestations in congenital toxoplasmosis range from asymptomatic or mild-medium disease forms to severe forms (4%), with serious neurological sequelae or even death." @default.
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- W3021400688 date "2020-01-01" @default.
- W3021400688 modified "2023-09-26" @default.
- W3021400688 title "Congenital toxoplasmosis – clinico-evolutive aspects" @default.
- W3021400688 doi "https://doi.org/10.26416/pedi.57.1.2020.3072" @default.
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