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- W3021520559 abstract "In decision making regarding optimal resource alloc ation to safeguard public health, policymakers and healthcare providers rely on the availability a nd reliability of data about the relative costs and benefits of competing treatment options. One such a n approach is based on cost effectiveness analysis (CEA) which is intended to be used as a co mbined metric of both the costs and health outcomes of alternative intervention strategies. Ho wever, the usual measures used in CEA are not readily analyzable based on standard statistical pa radigms for inference. Further, reliable data may not always be available to estimate relevant parame ters. Accordingly, it is essential to employ nonstandard procedures to compensate for information gaps and to address inferential difficulties. In this paper, we outline the issues associated wit h some of the commonly used techniques, with particular emphasis on the so-called network meta-a nalysis and indirect comparisons. Additional reference is made to the complexities introduced wh en data are used from observational studies. It is concluded that effective use of CEA in healthcar e policy presupposes a careful appreciation of the underlying issues, and implementation of robust remedial measures to mitigate their impacts." @default.
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- W3021520559 date "2014-01-01" @default.
- W3021520559 modified "2023-09-24" @default.
- W3021520559 title "Methodological Considerations in Cost-Effectiveness Analysis" @default.
- W3021520559 hasPublicationYear "2014" @default.
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