Matches in SemOpenAlex for { <https://semopenalex.org/work/W3021530091> ?p ?o ?g. }
- W3021530091 endingPage "75" @default.
- W3021530091 startingPage "59" @default.
- W3021530091 abstract "Abstract Natural scenes contain complex visual cues with specific features, including color, motion, flicker, and position. It is critical to understand how different visual features are processed at the early stages of visual perception to elicit appropriate cellular responses, and even behavioral output. Here, we studied the visual orientation response induced by flickering stripes in a novel behavioral paradigm in Drosophila melanogaster . We found that free walking flies exhibited bandpass orientation response to flickering stripes of different frequencies. The most sensitive frequency spectrum was confined to low frequencies of 2–4 Hz. Through genetic silencing, we showed that lamina L1 and L2 neurons, which receive visual inputs from R1 to R6 neurons, were the main components in mediating flicker‐induced orientation behavior. Moreover, specific blocking of different types of lamina feedback neurons Lawf1, Lawf2, C2, C3, and T1 modulated orientation responses to flickering stripes of particular frequencies, suggesting that bandpass orientation response was generated through cooperative modulation of lamina feedback neurons. Furthermore, we found that lamina feedback neurons Lawf1 were glutamatergic. Thermal activation of Lawf1 neurons could suppress neural activities in L1 and L2 neurons, which could be blocked by the glutamate‐gated chloride channel inhibitor picrotoxin (PTX). In summary, lamina monopolar neurons L1 and L2 are the primary components in mediating flicker‐induced orientation response. Meanwhile, lamina feedback neurons cooperatively modulate the orientation response in a frequency‐dependent way, which might be achieved through modulating neural activities of L1 and L2 neurons. image" @default.
- W3021530091 created "2020-05-13" @default.
- W3021530091 creator A5004286439 @default.
- W3021530091 creator A5004398523 @default.
- W3021530091 creator A5005801799 @default.
- W3021530091 creator A5028913379 @default.
- W3021530091 creator A5047365416 @default.
- W3021530091 creator A5063481044 @default.
- W3021530091 creator A5064101924 @default.
- W3021530091 creator A5068602784 @default.
- W3021530091 creator A5068962443 @default.
- W3021530091 creator A5073433104 @default.
- W3021530091 creator A5074513709 @default.
- W3021530091 creator A5075660795 @default.
- W3021530091 date "2020-06-25" @default.
- W3021530091 modified "2023-10-16" @default.
- W3021530091 title "Lamina feedback neurons regulate the bandpass property of the flicker‐induced orientation response in<i>Drosophila</i>" @default.
- W3021530091 cites W1485233858 @default.
- W3021530091 cites W1492732670 @default.
- W3021530091 cites W1519349329 @default.
- W3021530091 cites W1595045726 @default.
- W3021530091 cites W1829875163 @default.
- W3021530091 cites W1929289657 @default.
- W3021530091 cites W1964258072 @default.
- W3021530091 cites W1965453664 @default.
- W3021530091 cites W1967800066 @default.
- W3021530091 cites W1972455078 @default.
- W3021530091 cites W1972689388 @default.
- W3021530091 cites W1979641847 @default.
- W3021530091 cites W1989621138 @default.
- W3021530091 cites W1993835471 @default.
- W3021530091 cites W1994291744 @default.
- W3021530091 cites W1994855515 @default.
- W3021530091 cites W1995916301 @default.
- W3021530091 cites W1998105194 @default.
- W3021530091 cites W2000271306 @default.
- W3021530091 cites W2001551561 @default.
- W3021530091 cites W2012744590 @default.
- W3021530091 cites W2016682729 @default.
- W3021530091 cites W2017498277 @default.
- W3021530091 cites W2017603864 @default.
- W3021530091 cites W2017623030 @default.
- W3021530091 cites W2018082437 @default.
- W3021530091 cites W2018307984 @default.
- W3021530091 cites W2023874864 @default.
- W3021530091 cites W2029740022 @default.
- W3021530091 cites W2033572282 @default.
- W3021530091 cites W2035593030 @default.
- W3021530091 cites W2035654944 @default.
- W3021530091 cites W2036876463 @default.
- W3021530091 cites W2037283900 @default.
- W3021530091 cites W2037932249 @default.
- W3021530091 cites W2040852624 @default.
- W3021530091 cites W2050361994 @default.
- W3021530091 cites W2054266716 @default.
- W3021530091 cites W2063313724 @default.
- W3021530091 cites W2063565171 @default.
- W3021530091 cites W2065574450 @default.
- W3021530091 cites W2070154123 @default.
- W3021530091 cites W2070786476 @default.
- W3021530091 cites W2079250067 @default.
- W3021530091 cites W2079750030 @default.
- W3021530091 cites W2079852022 @default.
- W3021530091 cites W2079937287 @default.
- W3021530091 cites W2080529326 @default.
- W3021530091 cites W2082705554 @default.
- W3021530091 cites W2083890928 @default.
- W3021530091 cites W2088981001 @default.
- W3021530091 cites W2091116023 @default.
- W3021530091 cites W2091837964 @default.
- W3021530091 cites W2095080219 @default.
- W3021530091 cites W2104842125 @default.
- W3021530091 cites W2111748868 @default.
- W3021530091 cites W2118652401 @default.
- W3021530091 cites W2118830044 @default.
- W3021530091 cites W2122767334 @default.
- W3021530091 cites W2133006601 @default.
- W3021530091 cites W2135710940 @default.
- W3021530091 cites W2137813524 @default.
- W3021530091 cites W2139587743 @default.
- W3021530091 cites W2146025280 @default.
- W3021530091 cites W2151803127 @default.
- W3021530091 cites W2151886938 @default.
- W3021530091 cites W2152906974 @default.
- W3021530091 cites W2159817218 @default.
- W3021530091 cites W2189723131 @default.
- W3021530091 cites W2296157366 @default.
- W3021530091 cites W2489568129 @default.
- W3021530091 cites W2587878891 @default.
- W3021530091 cites W2588158303 @default.
- W3021530091 cites W2807798687 @default.
- W3021530091 cites W2901002348 @default.
- W3021530091 cites W2941680869 @default.
- W3021530091 cites W2952856895 @default.
- W3021530091 cites W2974015364 @default.
- W3021530091 cites W2999498932 @default.
- W3021530091 cites W3015240209 @default.
- W3021530091 doi "https://doi.org/10.1111/jnc.15036" @default.