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- W3021535330 abstract "Abstract The pathogenesis of the diabetic foot ulcer (DFU) is very complex. Among other known factors, such as poor innervation and vascularization, chronic infection and inflammation are critical factors that result in chronicity of these wounds. Novel and emerging concepts in chronic infection and inflammatory response are discussed in this chapter. Lack of adequate solutions for treatment of chronic wound infections such as antibiotic resistant and biofilm infections may result in serious consequences, including poor quality of life and amputations in patients with diabetes. Novel solutions that can counter these threats are urgently needed. A thorough understanding of the principles of immune dysfunction and insufficient resolution of inflammation will lead to innovative interventions that can drive a diabetic wound towards resolution of inflammation, which is conducive to healing." @default.
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- W3021535330 date "2020-01-01" @default.
- W3021535330 modified "2023-10-14" @default.
- W3021535330 title "Chronic infection and inflammation: Hallmarks of diabetic foot ulcers" @default.
- W3021535330 doi "https://doi.org/10.1016/b978-0-12-816413-6.00003-4" @default.
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