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- W3021567105 abstract "The present report describes one-pot three-component condensation of isatins, malononitrile, and 2-hydroxy-4 H-pyrimido[2,1- b][1,3]benzothiazol-4-one in water–ethanol mixture at reflux to develop an efficient one-pot protocol for the synthesis of novel spiro[indole-3,4′-pyrano[2′,3′:4,5]pyrimido[2,1- b][1,3]benzothiazole] derivatives. The significant features of this protocol are short reaction times, avoidance of toxic catalysts, and provision of excellent yields, no column chromatographic purification, and use of ethanol-water as an environmentally benign solvent. The molecular structure of 4a has been supported by single-crystal X-ray diffraction." @default.
- W3021567105 created "2020-05-13" @default.
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- W3021567105 creator A5054595603 @default.
- W3021567105 date "2020-04-29" @default.
- W3021567105 modified "2023-09-24" @default.
- W3021567105 title "One-pot, catalyst-free synthesis of novel spiro[indole-3,4′-pyrano[2′,3′:4,5]pyrimido [2,1-<i>b</i>][1,3]benzothiazole] derivatives" @default.
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- W3021567105 doi "https://doi.org/10.1177/1747519820916926" @default.
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