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- W3021569359 abstract "Introduction Population level data on complications and outcomes of pancreaticobiliary (PB) endoscopic ultrasound (EUS) are limited. A perforation rate of 0.03% and attributable morbidity and mortality from pancreatic EUS fine needle aspiration (FNA) of 2.4% and 0.02% respectively are reported. We have examined PB EUS & FNA use in England, how it relates to pancreatic cancer (PC) therapy and associated mortality and adverse events. Methods Adults undergoing PB EUS from 2007–17 were identified in Hospital Episode Statistics. A PC diagnosis within 6 months of EUS was required for PC cohort inclusion. EUS and FNA numbers per year, associated 7-day adverse events and 30-day mortality were examined. A logistic regression model examined the impact of variables on mortality and surgical resection. Results 79,490 PB EUS in 69,120 subjects were identified. The number per year increased from 2,915 (29% FNA) to 12,764 (35% FNA) over the study period. 8,859 subjects were diagnosed with PC. Bleeding was coded in 0.4% of PB EUS. Perforation was coded in 0.03% and in 0.05% of the PC cohort. 1.6% of PB EUS subjects and 2.8% in the PC cohort died within 30 days of their final EUS. The following factors were associated with increased mortality: increasing age (odds ratio 1.04(95%CI 1.03–1.04),p 782 EUS] 8–111 (3.99 (2.95–5.38), p 32.9% of PC subjects had a surgical resection, 43.1% received chemotherapy alone and 33.1% had no active therapy. Increasing age (0.97(95%CI 0.96–0.97), p Conclusions The number of PB-EUS undertaken in England has increased six-fold over the last decade, with an increased proportion of FNA. Deprivation and low provider volume were associated with 30 day mortality. A third of subjects undergoing PB EUS for PC did not receive surgery or chemotherapy. The results of this study support a reappraisal of the provision of and indications for PB EUS." @default.
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- W3021569359 date "2019-06-01" @default.
- W3021569359 modified "2023-09-23" @default.
- W3021569359 title "OTU-03 Pancreaticobiliary endoscopic ultrasound in england 2007–2017: changing practice, benefits and harms" @default.
- W3021569359 doi "https://doi.org/10.1136/gutjnl-2019-bsgabstracts.3" @default.
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