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- W3021584085 abstract "The first description of the use of an intravenous local anesthetic as an analgesic appeared over 60 years ago. Many reports since then have confirmed this effect and yet the use of intravenous local anesthetics have not become widespread practice. In a study of twenty adult patients with chronic pain of mixed etiology (including neuropathic pain and fibromyalgia), each patient received an intravenous infusion of 1200mg of lidocaine over 12 hours, pain scores 10cm LVAS) fell from a pretreatment average of 7.8 to a daily average of 4.4 for the first week and daily averages of 4.1, 3.9, 3.5,4.2 and 5.8 for the second, third, fourth and fifth weeks. Average daily number of analgesic tablets fell from 7.1 to a dailt average of 4.8 in the first week. This decreased anagesic consumption persisted for 5 weeks. No patient complianed of any adverse effect during or after the infusion period. Therefore, a single intravenous infusion of lidocaine over a 12 hour period produced pain relief that persisted for five weeks with was accompanied by a significant reduction in analgesic consumption. Lidocaine is cheapp, and if the results of this small study are correct, an effective method of producing pain relief associated with few adverse effects." @default.
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- W3021584085 date "2006-04-01" @default.
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- W3021584085 title "(750)" @default.
- W3021584085 doi "https://doi.org/10.1016/j.jpain.2006.01.152" @default.
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