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- W3021609946 abstract "While stress can precipitate the onset of psychiatric disorders in some individuals, others escape these conditions, an ability defined as resilience. In the chronic social defeat stress model (CSDS), the locus coeruleus-noradrenergic (LC-NE) system appears essential for resilience via its downstream inhibition of dopaminergic neurons. However, its contribution in resilience against different stress modalities is unclear. Our objective is to define how resilience is dependent upon the noradrenergic system in the learned helplessness (LH) paradigm, based on the avoidance of a previously inescapable footshock." @default.
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- W3021609946 date "2020-05-01" @default.
- W3021609946 modified "2023-09-30" @default.
- W3021609946 title "Noradrenergic System Variability in Resilience Against Stress" @default.
- W3021609946 doi "https://doi.org/10.1016/j.biopsych.2020.02.352" @default.
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