Matches in SemOpenAlex for { <https://semopenalex.org/work/W3021648875> ?p ?o ?g. }
Showing items 1 to 81 of
81
with 100 items per page.
- W3021648875 abstract "Background Current referral pathways in Australia for colorectal cancer (CRC) screening do not differentiate well between low and high-risk populations, and therefore may not be efficiently utilising resources. Whilst multiple CRC risk scoring systems currently exist and are utilised to stratify patients into low and high risk groups for priority of colorectal screening, there remains a need to identify which system has the greatest diagnostic accuracy. Therefore, we prospectively compared three existing CRC risk score systems in their ability to predict advanced colorectal neoplasia in Australian population; the Asia-Pacific Colorectal Screening (APCS) score; Hong Kong Score (2014); and Imperiale Score (2015). Methods Patients scheduled for colonoscopy assessment, both with or without gastrointestinal symptoms, were recruited. FOBT positive patients were included, but those who had an examination of the colon, including colonoscopy, within the last five years were excluded. Univariate and multivariate logistic regression was applied to identify significant risk factors for advanced neoplasia. For each patient, the 3 different risk scores were applied and the performance of each score in the prediction of advanced neoplasia was compared by examining the area under the curve (AUC) value. Results A total of 361 patients undergoing colonoscopy (48.2% male, median age 60 years) were prospectively recruited. The prevalence of adenomas was 31.6%, and 10.0% for advanced adenoma including 8 CRC (2.2%). Upon multivariate analysis, age and male sex were found to be significant risk factors (P=0.001, P=0.002). For predicting the prevalence of advanced neoplasia, the APCS score had AUC 0.71 (95%CI 0.63–0.79), Hong Kong Score 0.69 (95%CI 0.61–0.78), and Imperiale Score 0.68 (95%CI 0.59–0.77). Using a non-parametric comparison of the AUCs, there was no statistical significance between each of the scores for both symptomatic and asymptomatic populations (P=0.37 for APCS vs Hong Kong Score; P=0.32 for APCS vs Imperiale Score; P=0.43 for Hong Kong Score vs Imperiale Score). Conclusions All three scores are equally effective in stratifying the population into low and high risk colorectal neoplasia groups, and may be used to prioritise patients for colorectal screening." @default.
- W3021648875 created "2020-05-13" @default.
- W3021648875 creator A5007546776 @default.
- W3021648875 creator A5020598469 @default.
- W3021648875 creator A5041706697 @default.
- W3021648875 creator A5059745749 @default.
- W3021648875 date "2019-06-01" @default.
- W3021648875 modified "2023-09-24" @default.
- W3021648875 title "IDDF2019-ABS-0042 Prospective study of risk score strategies in the prediction of advanced colorectal neoplasia at colonoscopy" @default.
- W3021648875 doi "https://doi.org/10.1136/gutjnl-2019-iddfabstracts.6" @default.
- W3021648875 hasPublicationYear "2019" @default.
- W3021648875 type Work @default.
- W3021648875 sameAs 3021648875 @default.
- W3021648875 citedByCount "0" @default.
- W3021648875 crossrefType "proceedings-article" @default.
- W3021648875 hasAuthorship W3021648875A5007546776 @default.
- W3021648875 hasAuthorship W3021648875A5020598469 @default.
- W3021648875 hasAuthorship W3021648875A5041706697 @default.
- W3021648875 hasAuthorship W3021648875A5059745749 @default.
- W3021648875 hasBestOaLocation W30216488751 @default.
- W3021648875 hasConcept C11783203 @default.
- W3021648875 hasConcept C121608353 @default.
- W3021648875 hasConcept C126322002 @default.
- W3021648875 hasConcept C143998085 @default.
- W3021648875 hasConcept C144301174 @default.
- W3021648875 hasConcept C151956035 @default.
- W3021648875 hasConcept C188816634 @default.
- W3021648875 hasConcept C2776135927 @default.
- W3021648875 hasConcept C2777428134 @default.
- W3021648875 hasConcept C2778435480 @default.
- W3021648875 hasConcept C2779134260 @default.
- W3021648875 hasConcept C2908647359 @default.
- W3021648875 hasConcept C38180746 @default.
- W3021648875 hasConcept C512399662 @default.
- W3021648875 hasConcept C526805850 @default.
- W3021648875 hasConcept C71924100 @default.
- W3021648875 hasConcept C99454951 @default.
- W3021648875 hasConceptScore W3021648875C11783203 @default.
- W3021648875 hasConceptScore W3021648875C121608353 @default.
- W3021648875 hasConceptScore W3021648875C126322002 @default.
- W3021648875 hasConceptScore W3021648875C143998085 @default.
- W3021648875 hasConceptScore W3021648875C144301174 @default.
- W3021648875 hasConceptScore W3021648875C151956035 @default.
- W3021648875 hasConceptScore W3021648875C188816634 @default.
- W3021648875 hasConceptScore W3021648875C2776135927 @default.
- W3021648875 hasConceptScore W3021648875C2777428134 @default.
- W3021648875 hasConceptScore W3021648875C2778435480 @default.
- W3021648875 hasConceptScore W3021648875C2779134260 @default.
- W3021648875 hasConceptScore W3021648875C2908647359 @default.
- W3021648875 hasConceptScore W3021648875C38180746 @default.
- W3021648875 hasConceptScore W3021648875C512399662 @default.
- W3021648875 hasConceptScore W3021648875C526805850 @default.
- W3021648875 hasConceptScore W3021648875C71924100 @default.
- W3021648875 hasConceptScore W3021648875C99454951 @default.
- W3021648875 hasLocation W30216488751 @default.
- W3021648875 hasOpenAccess W3021648875 @default.
- W3021648875 hasPrimaryLocation W30216488751 @default.
- W3021648875 hasRelatedWork W1864374157 @default.
- W3021648875 hasRelatedWork W1973508424 @default.
- W3021648875 hasRelatedWork W2015052783 @default.
- W3021648875 hasRelatedWork W2067789806 @default.
- W3021648875 hasRelatedWork W2078296061 @default.
- W3021648875 hasRelatedWork W2085598712 @default.
- W3021648875 hasRelatedWork W2109822355 @default.
- W3021648875 hasRelatedWork W2123837974 @default.
- W3021648875 hasRelatedWork W2160691976 @default.
- W3021648875 hasRelatedWork W2162190655 @default.
- W3021648875 hasRelatedWork W2188891293 @default.
- W3021648875 hasRelatedWork W2518211924 @default.
- W3021648875 hasRelatedWork W2617009808 @default.
- W3021648875 hasRelatedWork W2788875817 @default.
- W3021648875 hasRelatedWork W2999935349 @default.
- W3021648875 hasRelatedWork W3022812136 @default.
- W3021648875 hasRelatedWork W3082299081 @default.
- W3021648875 hasRelatedWork W3161780265 @default.
- W3021648875 hasRelatedWork W3200629878 @default.
- W3021648875 hasRelatedWork W1964440284 @default.
- W3021648875 isParatext "false" @default.
- W3021648875 isRetracted "false" @default.
- W3021648875 magId "3021648875" @default.
- W3021648875 workType "article" @default.