Matches in SemOpenAlex for { <https://semopenalex.org/work/W3021796280> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W3021796280 abstract "Abstract The mesentery is the organ that supports development of all abdominal digestive organs in the foetus, and which supports and maintains all abdominal digestive organs in systemic continuity in the adult. Mesenteric abnormalities such as creeping fat are pathognomic of Crohn's disease and point to a pathobiological role for the mesentery. As part of the standard operative approach to resection, the mesentery is normally retained. Recent observations suggest that if the mesentery is included in the resections for ileocolic Crohn's disease, postoperative requirements for re-operation may be reduced. This is supported by emerging observations related to excision of the mesorectum during proctectomy for Crohn's disease, and by observations on the Kono-S procedure. As part of the latter, the mesentery is retained but is circumferentially excluded from the intestinal anastomosis. Mesenteric resection may also provide a more oncologically sound approach, in patients who also harbour a malignancy. Concerns regarding mesenteric resection relate to the possibility of mesenteric haemorrhage, and the lack of surgical planes in a hostile operative setting. Reliable haemostatic techniques have emerged that enable safe mesenteric division. Emerging data that support a staged approach to mesenteric resection, in complex operative settings. Increasing studies characterise the cellular and molecular basis of the net pathogenic effects of the mesentery. These could provide pharmacotherapeutic opportunities for the future avoidance of surgery. This article discusses the position of the mesentery in the pathobiology of Crohn's disease, and surgical strategies that alter mesenteric inputs." @default.
- W3021796280 created "2020-05-13" @default.
- W3021796280 creator A5020550801 @default.
- W3021796280 creator A5048691800 @default.
- W3021796280 date "2020-06-01" @default.
- W3021796280 modified "2023-09-26" @default.
- W3021796280 title "Potential roles of the mesentery in Crohn's disease" @default.
- W3021796280 cites W1546880496 @default.
- W3021796280 cites W1964867477 @default.
- W3021796280 cites W1977950784 @default.
- W3021796280 cites W2015362372 @default.
- W3021796280 cites W2043065550 @default.
- W3021796280 cites W2049596761 @default.
- W3021796280 cites W2081931036 @default.
- W3021796280 cites W2115507998 @default.
- W3021796280 cites W2129342823 @default.
- W3021796280 cites W2144090579 @default.
- W3021796280 cites W2161685971 @default.
- W3021796280 cites W2212173009 @default.
- W3021796280 cites W2343116742 @default.
- W3021796280 cites W2466055226 @default.
- W3021796280 cites W2531692255 @default.
- W3021796280 cites W2606184163 @default.
- W3021796280 cites W2613397238 @default.
- W3021796280 cites W2745687892 @default.
- W3021796280 cites W2746085822 @default.
- W3021796280 cites W2791820110 @default.
- W3021796280 cites W2792917444 @default.
- W3021796280 cites W2809106943 @default.
- W3021796280 cites W2823978773 @default.
- W3021796280 cites W2883401635 @default.
- W3021796280 cites W2888121871 @default.
- W3021796280 cites W2892321262 @default.
- W3021796280 cites W2896373909 @default.
- W3021796280 cites W2897196041 @default.
- W3021796280 cites W2897678431 @default.
- W3021796280 cites W2898151951 @default.
- W3021796280 cites W2898396048 @default.
- W3021796280 cites W2906351324 @default.
- W3021796280 cites W2930934769 @default.
- W3021796280 cites W2937171139 @default.
- W3021796280 cites W2948542723 @default.
- W3021796280 cites W2955181112 @default.
- W3021796280 cites W2972797205 @default.
- W3021796280 cites W71681599 @default.
- W3021796280 doi "https://doi.org/10.1016/j.scrs.2020.100743" @default.
- W3021796280 hasPublicationYear "2020" @default.
- W3021796280 type Work @default.
- W3021796280 sameAs 3021796280 @default.
- W3021796280 citedByCount "0" @default.
- W3021796280 crossrefType "journal-article" @default.
- W3021796280 hasAuthorship W3021796280A5020550801 @default.
- W3021796280 hasAuthorship W3021796280A5048691800 @default.
- W3021796280 hasConcept C141071460 @default.
- W3021796280 hasConcept C142724271 @default.
- W3021796280 hasConcept C2778948390 @default.
- W3021796280 hasConcept C2779134260 @default.
- W3021796280 hasConcept C2779280984 @default.
- W3021796280 hasConcept C2779399171 @default.
- W3021796280 hasConcept C61434518 @default.
- W3021796280 hasConcept C71924100 @default.
- W3021796280 hasConcept C8443397 @default.
- W3021796280 hasConceptScore W3021796280C141071460 @default.
- W3021796280 hasConceptScore W3021796280C142724271 @default.
- W3021796280 hasConceptScore W3021796280C2778948390 @default.
- W3021796280 hasConceptScore W3021796280C2779134260 @default.
- W3021796280 hasConceptScore W3021796280C2779280984 @default.
- W3021796280 hasConceptScore W3021796280C2779399171 @default.
- W3021796280 hasConceptScore W3021796280C61434518 @default.
- W3021796280 hasConceptScore W3021796280C71924100 @default.
- W3021796280 hasConceptScore W3021796280C8443397 @default.
- W3021796280 hasLocation W30217962801 @default.
- W3021796280 hasOpenAccess W3021796280 @default.
- W3021796280 hasPrimaryLocation W30217962801 @default.
- W3021796280 hasRelatedWork W10594257 @default.
- W3021796280 hasRelatedWork W10726170 @default.
- W3021796280 hasRelatedWork W11796118 @default.
- W3021796280 hasRelatedWork W13185387 @default.
- W3021796280 hasRelatedWork W1527787 @default.
- W3021796280 hasRelatedWork W18240430 @default.
- W3021796280 hasRelatedWork W1930163 @default.
- W3021796280 hasRelatedWork W20624640 @default.
- W3021796280 hasRelatedWork W6971197 @default.
- W3021796280 hasRelatedWork W18144788 @default.
- W3021796280 isParatext "false" @default.
- W3021796280 isRetracted "false" @default.
- W3021796280 magId "3021796280" @default.
- W3021796280 workType "article" @default.