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- W3021803604 abstract "This chapter discusses the clinical features and treatment of disorders of the portal and hepatic venous systems such as portal hypertension, portal vein obstruction, intrahepatic portal hypertension, post-hepatic portal hypertension, Budd-Chiari syndrome and veno-occlusive disease of the liver. Portal hypertension is the major feature of disorders of the portal and hepatic venous systems. Hepatic vein lesions also cause acute or chronic liver failure. Portal hypertension exists when the pressure in the portal venous system rises above 10–12 mmHg. Portal hypertension may arise due to pre-, intra-, or post-hepatic obstruction of blood flow to and through the liver. The intrahepatic block may be pre-sinusoidal, sinusoidal or post-sinusoidal. Rarely, portal hypertension results from increased blood flow to the liver from arteriovenous anastomosis. Cirrhosis, portal vein obstruction, congenital hepatic fibrosis, and hepatic vein outflow obstruction are the main causes of portal hypertension in children. It may also present with features of the underlying hepatic disease of which it is a complication. In portal vein obstruction the main portal vein or splenic vein is obstructed somewhere along its course, between the hilum of the spleen and the portahepatis. The portal vein may be replaced by a fibrous remnant, a sheaf of small channels usually described as cavernous transformation, or contain an organized blood clot, web or diaphragm or be compressed from outside. Portal vein obstruction may be strongly suspected if an experienced ultrasonographer is unable to demonstrate a patent portal vein in a patient with the above features and biochemical tests of liver function are normal." @default.
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- W3021803604 date "1994-01-01" @default.
- W3021803604 modified "2023-09-27" @default.
- W3021803604 title "Disorders of the portal and hepatic venous systems" @default.
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- W3021803604 doi "https://doi.org/10.1016/b978-0-7506-1039-1.50028-3" @default.
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