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- W3021846338 abstract "Combination of water extract of Andrographis paniculata and water extract of Syzygium polyanthum (6:1) have been reported to reduce blood glucose in normal and alloxan rats. This combination also gave protection effects on kidney, liver and pancreas animals tested from alloxan toxicityMethods : Eighty male white albino rats were divided into eight different groups including normal control,diabetic control, 4 treated groups with the water extract of Andrographis paniculata, water extract of Syzygium polyanthum and its combination, and also standard drugs (metformin, insulin) with 10 rats in each group. The extracts and the standard were given orally for 7 days. At day 7 blood sample was collecte'd, serum separated and glycemic level, total cholesterol, LDL, HDL, triglyceride, and alkaline phosphatase were determined. The body weight was recorded on day 1 and day 7.Results and discussion: The data obtained revealed that the water extract of Andrographis paniculata(WAP), water extract of Syzygium polyanthum (WSP) and its combination (1 WAP: 6 WSP; 6 WAP:1 WSP) reduced the glucose level. The treatment with these extracts also reduced the LDL and triglyceride level significantly and alkaline phospatase level as compared with normal and diabetic groups.Conclusions: The water extract of Andrographis paniculata, water extract of Syzygium polyanthum and itscombination possess significant antidiabetic activity along with antihypercholesterolemic activity.Key words: Andrographis paniculata, Syzygium polyanthum, water extracts, antidiabetic,antihypercholesterolemic" @default.
- W3021846338 created "2020-05-13" @default.
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- W3021846338 date "2014-04-01" @default.
- W3021846338 modified "2023-09-27" @default.
- W3021846338 title "The Lipid Lowering Effect of Water Extract of Andrographis paniculata, Water Extract of Syzigium polyanthum and its Combination in Alloxan-Induced Diabetic Rats" @default.
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