Matches in SemOpenAlex for { <https://semopenalex.org/work/W3021886220> ?p ?o ?g. }
- W3021886220 endingPage "216" @default.
- W3021886220 startingPage "216" @default.
- W3021886220 abstract "Despite the availability of an effective preventive vaccine for hepatitis B virus (HBV) for over 38 years, chronic HBV (CHB) infection remains a global health burden with around 257 million patients. The ideal treatment goal for CHB infection would be to achieve complete cure; however, current therapies such as peg-interferon and nucleos(t)ide analogs are unable to achieve the functional cure, the newly set target for HBV chronic infection. Considering the fact functional cure has been accepted as an endpoint in the treatment of chronic hepatitis B by scientific committee, the development of alternative therapeutic strategies is urgently needed to functionally cure CHB infection. A promising target for future therapeutic strategies is immune modulation to restore dysfunctional HBV-specific immunity. In this review, we provide an overview of the progress in alternative therapeutic strategies, including immune-based therapeutic approaches that enhance host innate and adaptive immunity to achieve and increase the functional cure from CHB infection." @default.
- W3021886220 created "2020-05-13" @default.
- W3021886220 creator A5002454451 @default.
- W3021886220 creator A5004798738 @default.
- W3021886220 creator A5022430910 @default.
- W3021886220 creator A5081133571 @default.
- W3021886220 date "2020-05-11" @default.
- W3021886220 modified "2023-09-25" @default.
- W3021886220 title "Targeting Host Innate and Adaptive Immunity to Achieve the Functional Cure of Chronic Hepatitis B" @default.
- W3021886220 cites W1024473 @default.
- W3021886220 cites W1518036601 @default.
- W3021886220 cites W1522136588 @default.
- W3021886220 cites W1582382237 @default.
- W3021886220 cites W1771539945 @default.
- W3021886220 cites W1799137450 @default.
- W3021886220 cites W1906279869 @default.
- W3021886220 cites W1919093559 @default.
- W3021886220 cites W1961215690 @default.
- W3021886220 cites W1965315469 @default.
- W3021886220 cites W1974257643 @default.
- W3021886220 cites W1975441426 @default.
- W3021886220 cites W1983251878 @default.
- W3021886220 cites W1985701752 @default.
- W3021886220 cites W1987376967 @default.
- W3021886220 cites W1999770898 @default.
- W3021886220 cites W2000307707 @default.
- W3021886220 cites W2002258333 @default.
- W3021886220 cites W2004465286 @default.
- W3021886220 cites W2006774237 @default.
- W3021886220 cites W2008517556 @default.
- W3021886220 cites W2008866474 @default.
- W3021886220 cites W2009430008 @default.
- W3021886220 cites W2009897436 @default.
- W3021886220 cites W2011736290 @default.
- W3021886220 cites W2012025617 @default.
- W3021886220 cites W2012090731 @default.
- W3021886220 cites W2014495927 @default.
- W3021886220 cites W2015760225 @default.
- W3021886220 cites W2015763479 @default.
- W3021886220 cites W2023366700 @default.
- W3021886220 cites W2027555120 @default.
- W3021886220 cites W2031913105 @default.
- W3021886220 cites W2050385094 @default.
- W3021886220 cites W2051173965 @default.
- W3021886220 cites W2052099238 @default.
- W3021886220 cites W2052217197 @default.
- W3021886220 cites W2053259740 @default.
- W3021886220 cites W2055002900 @default.
- W3021886220 cites W2055270948 @default.
- W3021886220 cites W2056215929 @default.
- W3021886220 cites W2056877436 @default.
- W3021886220 cites W2059522845 @default.
- W3021886220 cites W2060021952 @default.
- W3021886220 cites W2064823659 @default.
- W3021886220 cites W2070715664 @default.
- W3021886220 cites W2072656296 @default.
- W3021886220 cites W2074597048 @default.
- W3021886220 cites W2077467499 @default.
- W3021886220 cites W2079656135 @default.
- W3021886220 cites W2087564721 @default.
- W3021886220 cites W2089108066 @default.
- W3021886220 cites W2091172564 @default.
- W3021886220 cites W2091703661 @default.
- W3021886220 cites W2096109794 @default.
- W3021886220 cites W2100258681 @default.
- W3021886220 cites W2101019626 @default.
- W3021886220 cites W2101032357 @default.
- W3021886220 cites W2102416504 @default.
- W3021886220 cites W2105853552 @default.
- W3021886220 cites W2106908798 @default.
- W3021886220 cites W2107057287 @default.
- W3021886220 cites W2107788106 @default.
- W3021886220 cites W2109816755 @default.
- W3021886220 cites W2117789841 @default.
- W3021886220 cites W2119139878 @default.
- W3021886220 cites W2120128540 @default.
- W3021886220 cites W2130357985 @default.
- W3021886220 cites W2136330473 @default.
- W3021886220 cites W2140921924 @default.
- W3021886220 cites W2145007235 @default.
- W3021886220 cites W2147134417 @default.
- W3021886220 cites W2147283902 @default.
- W3021886220 cites W2148216588 @default.
- W3021886220 cites W2152095262 @default.
- W3021886220 cites W2155254827 @default.
- W3021886220 cites W2156731130 @default.
- W3021886220 cites W2162260536 @default.
- W3021886220 cites W2162903981 @default.
- W3021886220 cites W2163553774 @default.
- W3021886220 cites W2166849716 @default.
- W3021886220 cites W2169631718 @default.
- W3021886220 cites W2171216965 @default.
- W3021886220 cites W2171393763 @default.
- W3021886220 cites W2198085199 @default.
- W3021886220 cites W2198678042 @default.
- W3021886220 cites W2266745237 @default.
- W3021886220 cites W2267571233 @default.
- W3021886220 cites W2337204897 @default.