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- W3022047906 abstract "Abstract The two‐mutation carcinogenesis model, better known as the two‐stage clonal expansion (TSCE) model, is a type of multistage carcinogenesis model that explicitly considers stochastic growth of intermediate cells on the pathway to malignancy. Because of this fact, this model can be used not only for analysis of time‐to‐tumor data, which requires the hazard function, but also for analysis of intermediate lesions, such as colon polyps, which requires expressions for the number and the size distribution of such lesions. The model has been extensively used for analyses of both types of data. Extensions of the model to incorporate more than two mutations have also been proposed." @default.
- W3022047906 created "2020-05-13" @default.
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- W3022047906 date "2005-02-15" @default.
- W3022047906 modified "2023-10-16" @default.
- W3022047906 title "Two‐Mutation Carcinogenesis Model" @default.
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- W3022047906 doi "https://doi.org/10.1002/0470011815.b2a07057" @default.
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