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- W3022097166 abstract "Osteoporosis is a metabolic disease that affects bone tissue and is highly associated with bone fractures. Typical osteoporosis fracture treatments, such as bisphosphonates and hormone replacement, present important challenges because of their low bioavailability on the site of action. Options to overcome this issue are systems for the local release of therapeutic agents such as bioactive glasses containing therapeutic molecules and ions. These agents are released during the dissolution process, combining the drugs and ion therapeutic effects for osteoporosis treatment. Among the therapeutic agents that can be applied for bone repair are strontium (Sr) ion and phytopharmaceutical icariin, which have shown potential to promote healthy bone marrow stem cells osteogenic differentiation, increase bone formation and prevent bone loss. Submicron Sr-containing bioactive glass mesoporous spheres with sustained ion release capacity were obtained. Icariin was successfully incorporated into the particles, and the glass composition influenced the icariin incorporation efficiency and release rates. In this work, for the first time, Sr and icariin were incorporated into bioactive glass submicron mesoporous spheres and the in vitro effects of the therapeutic agents release were evaluated on the reduced osteogenic potential of rat osteoporotic bone marrow mesenchymal stem cells, and results showed an improvement on the reduced differentiation potential." @default.
- W3022097166 created "2020-05-13" @default.
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- W3022097166 creator A5089778261 @default.
- W3022097166 date "2020-09-04" @default.
- W3022097166 modified "2023-10-14" @default.
- W3022097166 title "<i>In vitro</i> effects of the co-release of icariin and strontium from bioactive glass submicron spheres on the reduced osteogenic potential of rat osteoporotic bone marrow mesenchymal stem cells" @default.
- W3022097166 cites W1844334929 @default.
- W3022097166 cites W1965777032 @default.
- W3022097166 cites W1967222288 @default.
- W3022097166 cites W1968580734 @default.
- W3022097166 cites W1968844623 @default.
- W3022097166 cites W1974361804 @default.
- W3022097166 cites W1974733852 @default.
- W3022097166 cites W1975145454 @default.
- W3022097166 cites W1975428589 @default.
- W3022097166 cites W1975767364 @default.
- W3022097166 cites W1978355628 @default.
- W3022097166 cites W1982414211 @default.
- W3022097166 cites W1993296212 @default.
- W3022097166 cites W1996565709 @default.
- W3022097166 cites W1997274211 @default.
- W3022097166 cites W1999104118 @default.
- W3022097166 cites W2000212217 @default.
- W3022097166 cites W2002685309 @default.
- W3022097166 cites W2003926055 @default.
- W3022097166 cites W2010395830 @default.
- W3022097166 cites W2010732983 @default.
- W3022097166 cites W2012720436 @default.
- W3022097166 cites W2013950510 @default.
- W3022097166 cites W2014979591 @default.
- W3022097166 cites W2025371271 @default.
- W3022097166 cites W2026913920 @default.
- W3022097166 cites W2030299449 @default.
- W3022097166 cites W2032049669 @default.
- W3022097166 cites W2034602186 @default.
- W3022097166 cites W2034630426 @default.
- W3022097166 cites W2036669971 @default.
- W3022097166 cites W2037186348 @default.
- W3022097166 cites W2039418353 @default.
- W3022097166 cites W2039430435 @default.
- W3022097166 cites W2041878998 @default.
- W3022097166 cites W2047428956 @default.
- W3022097166 cites W2048003672 @default.
- W3022097166 cites W2048954481 @default.
- W3022097166 cites W2049601450 @default.
- W3022097166 cites W2058293286 @default.
- W3022097166 cites W2059675275 @default.
- W3022097166 cites W2060211276 @default.
- W3022097166 cites W2062772772 @default.
- W3022097166 cites W2062820788 @default.
- W3022097166 cites W2073865644 @default.
- W3022097166 cites W2074480129 @default.
- W3022097166 cites W2075335813 @default.
- W3022097166 cites W2079854906 @default.
- W3022097166 cites W2084378924 @default.
- W3022097166 cites W2085198567 @default.
- W3022097166 cites W2086962772 @default.
- W3022097166 cites W2125134725 @default.
- W3022097166 cites W2132010023 @default.
- W3022097166 cites W2137479138 @default.
- W3022097166 cites W2145271035 @default.
- W3022097166 cites W2154375318 @default.
- W3022097166 cites W2157956984 @default.
- W3022097166 cites W2174797893 @default.
- W3022097166 cites W2175641827 @default.
- W3022097166 cites W2191343050 @default.
- W3022097166 cites W2207408701 @default.
- W3022097166 cites W2223937245 @default.
- W3022097166 cites W2268193501 @default.
- W3022097166 cites W2318142576 @default.
- W3022097166 cites W2318517360 @default.
- W3022097166 cites W2334908311 @default.
- W3022097166 cites W2335640937 @default.
- W3022097166 cites W2345331929 @default.
- W3022097166 cites W2346490252 @default.
- W3022097166 cites W2592244207 @default.
- W3022097166 cites W2608127690 @default.
- W3022097166 cites W2612894585 @default.
- W3022097166 cites W2618974892 @default.
- W3022097166 cites W2743070893 @default.
- W3022097166 cites W2759792705 @default.
- W3022097166 cites W2799518769 @default.
- W3022097166 cites W2886840546 @default.
- W3022097166 cites W2892419488 @default.
- W3022097166 cites W2906443950 @default.
- W3022097166 cites W2919630428 @default.
- W3022097166 cites W2926047830 @default.
- W3022097166 cites W2936061419 @default.
- W3022097166 cites W843007777 @default.
- W3022097166 doi "https://doi.org/10.1088/1748-605x/ab9095" @default.
- W3022097166 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32375130" @default.
- W3022097166 hasPublicationYear "2020" @default.
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