FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3022101916> ?p ?o ?g. }

• W3022101916 endingPage "2211" @default.
• W3022101916 startingPage "2203" @default.
• W3022101916 abstract "Abstract Recent studies have drawn the attention to the link between alcohol use disorder and the presence of pain. Indeed, the correct management of pain in patients with a previous history of alcohol use disorder has been reported to decrease the risk of relapse in alcohol drinking, suggesting that in this prone population, pain may increase the vulnerability to relapse. Previous data in male rats revealed that inflammatory pain desensitizes mu-opioid receptors in the ventral tegmental area and increases intake of high doses of heroin. Owing to the relevant role of mu-opioid receptors in alcohol effects, we hypothesize that pain may also alter alcohol reinforcing properties and therefore affect alcohol relapse in male rats. Our microdialysis studies show that the presence of inflammatory pain blunted the increase of extracellular dopamine levels in the nucleus accumbens induced by 1.5 g/kg of ethanol (s.c.). Moreover, we also revealed that the administration of 52 nmol of ethanol into the ventral tegmental area failed to induce place preference only in inflammatory pain-suffering animals, and a higher dose (70 nmol) was necessary to reverse this effect. Finally, we evaluated the effect of inflammatory pain on the alcohol deprivation effect in long-term ethanol-experienced male rats. After 4 cycles of free ethanol intake and abstinence periods, inflammatory pain induced alcohol deprivation effect without affecting its magnitude. These intriguing data reveal the impact of pain on neurochemical and behavioral effects after alcohol administration but also underscore the necessity of finding an appropriate paradigm to determine the long-term behavioral consequences." @default.
• W3022101916 created "2020-05-13" @default.
• W3022101916 creator A5005710048 @default.
• W3022101916 creator A5025904990 @default.
• W3022101916 creator A5026255738 @default.
• W3022101916 creator A5048701428 @default.
• W3022101916 creator A5056818530 @default.
• W3022101916 creator A5066094646 @default.
• W3022101916 date "2020-05-04" @default.
• W3022101916 modified "2023-10-14" @default.
• W3022101916 title "Impaired alcohol-induced dopamine release in the nucleus accumbens in an inflammatory pain model: behavioral implications in male rats" @default.
• W3022101916 cites W1520279806 @default.
• W3022101916 cites W1822002712 @default.
• W3022101916 cites W1837898466 @default.
• W3022101916 cites W1945462274 @default.
• W3022101916 cites W1946198398 @default.
• W3022101916 cites W1971113914 @default.
• W3022101916 cites W1971985706 @default.
• W3022101916 cites W1981141287 @default.
• W3022101916 cites W1982683778 @default.
• W3022101916 cites W1989362268 @default.
• W3022101916 cites W1996880759 @default.
• W3022101916 cites W2001470706 @default.
• W3022101916 cites W2016115765 @default.
• W3022101916 cites W2018650997 @default.
• W3022101916 cites W2022537146 @default.
• W3022101916 cites W2050833089 @default.
• W3022101916 cites W2052158594 @default.
• W3022101916 cites W2055686502 @default.
• W3022101916 cites W2057758856 @default.
• W3022101916 cites W2078550615 @default.
• W3022101916 cites W2092913199 @default.
• W3022101916 cites W2098276764 @default.
• W3022101916 cites W2109597010 @default.
• W3022101916 cites W2116087648 @default.
• W3022101916 cites W2116439316 @default.
• W3022101916 cites W2124092054 @default.
• W3022101916 cites W2126184291 @default.
• W3022101916 cites W2163582947 @default.
• W3022101916 cites W2168236068 @default.
• W3022101916 cites W2179572204 @default.
• W3022101916 cites W2317056404 @default.
• W3022101916 cites W2486826632 @default.
• W3022101916 cites W2515665586 @default.
• W3022101916 cites W2518346255 @default.
• W3022101916 cites W2547975165 @default.
• W3022101916 cites W2557658390 @default.
• W3022101916 cites W2587222353 @default.
• W3022101916 cites W2782173468 @default.
• W3022101916 cites W2804904418 @default.
• W3022101916 cites W2806456116 @default.
• W3022101916 cites W2894909937 @default.
• W3022101916 cites W2922000881 @default.
• W3022101916 cites W2969186494 @default.
• W3022101916 cites W2999234526 @default.
• W3022101916 cites W3001064620 @default.
• W3022101916 doi "https://doi.org/10.1097/j.pain.0000000000001915" @default.
• W3022101916 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32379224" @default.
• W3022101916 hasPublicationYear "2020" @default.
• W3022101916 type Work @default.
• W3022101916 sameAs 3022101916 @default.
• W3022101916 citedByCount "10" @default.
• W3022101916 countsByYear W30221019162020 @default.
• W3022101916 countsByYear W30221019162021 @default.
• W3022101916 countsByYear W30221019162022 @default.
• W3022101916 countsByYear W30221019162023 @default.
• W3022101916 crossrefType "journal-article" @default.
• W3022101916 hasAuthorship W3022101916A5005710048 @default.
• W3022101916 hasAuthorship W3022101916A5025904990 @default.
• W3022101916 hasAuthorship W3022101916A5026255738 @default.
• W3022101916 hasAuthorship W3022101916A5048701428 @default.
• W3022101916 hasAuthorship W3022101916A5056818530 @default.
• W3022101916 hasAuthorship W3022101916A5066094646 @default.
• W3022101916 hasConcept C126322002 @default.
• W3022101916 hasConcept C134018914 @default.
• W3022101916 hasConcept C137183658 @default.
• W3022101916 hasConcept C170493617 @default.
• W3022101916 hasConcept C178790620 @default.
• W3022101916 hasConcept C185592680 @default.
• W3022101916 hasConcept C25876315 @default.
• W3022101916 hasConcept C2776552330 @default.
• W3022101916 hasConcept C2779436514 @default.
• W3022101916 hasConcept C2779442783 @default.
• W3022101916 hasConcept C2780161600 @default.
• W3022101916 hasConcept C2780948874 @default.
• W3022101916 hasConcept C2781063702 @default.
• W3022101916 hasConcept C2781066024 @default.
• W3022101916 hasConcept C2908647359 @default.
• W3022101916 hasConcept C42219234 @default.
• W3022101916 hasConcept C50156730 @default.
• W3022101916 hasConcept C513476851 @default.
• W3022101916 hasConcept C55493867 @default.
• W3022101916 hasConcept C71924100 @default.
• W3022101916 hasConcept C98274493 @default.
• W3022101916 hasConcept C99454951 @default.
• W3022101916 hasConceptScore W3022101916C126322002 @default.
• W3022101916 hasConceptScore W3022101916C134018914 @default.
• W3022101916 hasConceptScore W3022101916C137183658 @default.

• next