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• W3022121698 abstract "Herein, a rapid and sensitive current–volt measurement was developed for identifying the IS6110 DNA sequence to diagnose Mycobacterium tuberculosis (TB). An aminated capture probe was immobilized on a 1,1′-carbonyldiimidazole-functionalized interdigitated electrode (IDE) silica substrate, and the target sequence was detected by complementation. It was found that all tested concentrations displayed a higher response in current changes than the control, and the limit of detection was 10 fM. The sensitivity ranged from 1 to 10 fM. The control sequences with single-, triple-mismatch and noncomplementary sequences showed great discrimination. This rapid and easy DNA detection method helps to identify M. tuberculosis for early-stage diagnosis of TB." @default.
• W3022121698 created "2020-05-13" @default.
• W3022121698 creator A5016080102 @default.
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• W3022121698 date "2020-05-01" @default.
• W3022121698 modified "2023-10-14" @default.
• W3022121698 title "Targeted DNA complementation on a 1,1′-carbonyldiimidazole-functionalized surface for identifying Mycobacterium tuberculosis" @default.
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• W3022121698 doi "https://doi.org/10.1007/s13205-020-02216-2" @default.
• W3022121698 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7196115" @default.
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• W3022121698 hasPublicationYear "2020" @default.
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