Matches in SemOpenAlex for { <https://semopenalex.org/work/W3022207329> ?p ?o ?g. }
Showing items 1 to 93 of
93
with 100 items per page.
- W3022207329 endingPage "10" @default.
- W3022207329 startingPage "1" @default.
- W3022207329 abstract "Numerous G protein-coupled receptors (GPCRs) regulate multiple airway functions and play fundamental roles in normal and aberrant airway and lung physiology. Thus, GPCRs are prime candidates of targeting by disease therapeutics. The intriguing proton-sensing GPCR Ovarian cancer G-protein coupled receptor 1 (OGR1; aka GPR68) has recently been shown capable of regulating airway smooth muscle (ASM) contraction and proliferation. Although the study of OGR1 has been confounded by the fact that the proton is the presumed cognate ligand of OGR1, recent studies have begun to identify novel ligands and modulators capable of regulating the diverse signaling, and functional role of OGR1. Such studies offer hope for OGR1-targeting drugs as therapeutics for obstructive lung diseases such as asthma. Herein, we review the literature to date detailing the receptor biology and pharmacology of OGR1, receptor function in the airway, and describe the potential clinical utility of OGR1-modulating drugs." @default.
- W3022207329 created "2020-05-13" @default.
- W3022207329 creator A5023091621 @default.
- W3022207329 creator A5028310441 @default.
- W3022207329 date "2020-04-01" @default.
- W3022207329 modified "2023-10-11" @default.
- W3022207329 title "The proton-sensing receptor ovarian cancer G-protein coupled receptor 1 (OGR1) in airway physiology and disease" @default.
- W3022207329 cites W1698593587 @default.
- W3022207329 cites W1841743894 @default.
- W3022207329 cites W1899229346 @default.
- W3022207329 cites W1966908666 @default.
- W3022207329 cites W1976448487 @default.
- W3022207329 cites W1983081011 @default.
- W3022207329 cites W1985640372 @default.
- W3022207329 cites W1985929048 @default.
- W3022207329 cites W1990448891 @default.
- W3022207329 cites W1993398535 @default.
- W3022207329 cites W2005156999 @default.
- W3022207329 cites W2016553429 @default.
- W3022207329 cites W2027564266 @default.
- W3022207329 cites W2038184492 @default.
- W3022207329 cites W2039586729 @default.
- W3022207329 cites W2057646865 @default.
- W3022207329 cites W2059444030 @default.
- W3022207329 cites W2068522128 @default.
- W3022207329 cites W2076643673 @default.
- W3022207329 cites W2080319985 @default.
- W3022207329 cites W2086036081 @default.
- W3022207329 cites W2091220261 @default.
- W3022207329 cites W2092453096 @default.
- W3022207329 cites W2096003392 @default.
- W3022207329 cites W2109292444 @default.
- W3022207329 cites W2125957493 @default.
- W3022207329 cites W2126700319 @default.
- W3022207329 cites W2127970144 @default.
- W3022207329 cites W2150308335 @default.
- W3022207329 cites W2153472648 @default.
- W3022207329 cites W2259397374 @default.
- W3022207329 cites W2342560946 @default.
- W3022207329 cites W2473831097 @default.
- W3022207329 cites W2766142738 @default.
- W3022207329 cites W2907890485 @default.
- W3022207329 cites W2914457725 @default.
- W3022207329 cites W2917085813 @default.
- W3022207329 cites W2986170540 @default.
- W3022207329 cites W4255337810 @default.
- W3022207329 doi "https://doi.org/10.1016/j.coph.2020.03.004" @default.
- W3022207329 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7529780" @default.
- W3022207329 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32361614" @default.
- W3022207329 hasPublicationYear "2020" @default.
- W3022207329 type Work @default.
- W3022207329 sameAs 3022207329 @default.
- W3022207329 citedByCount "8" @default.
- W3022207329 countsByYear W30222073292020 @default.
- W3022207329 countsByYear W30222073292021 @default.
- W3022207329 countsByYear W30222073292022 @default.
- W3022207329 crossrefType "journal-article" @default.
- W3022207329 hasAuthorship W3022207329A5023091621 @default.
- W3022207329 hasAuthorship W3022207329A5028310441 @default.
- W3022207329 hasBestOaLocation W30222073292 @default.
- W3022207329 hasConcept C135285700 @default.
- W3022207329 hasConcept C170493617 @default.
- W3022207329 hasConcept C502942594 @default.
- W3022207329 hasConcept C54355233 @default.
- W3022207329 hasConcept C60644358 @default.
- W3022207329 hasConcept C86803240 @default.
- W3022207329 hasConceptScore W3022207329C135285700 @default.
- W3022207329 hasConceptScore W3022207329C170493617 @default.
- W3022207329 hasConceptScore W3022207329C502942594 @default.
- W3022207329 hasConceptScore W3022207329C54355233 @default.
- W3022207329 hasConceptScore W3022207329C60644358 @default.
- W3022207329 hasConceptScore W3022207329C86803240 @default.
- W3022207329 hasLocation W30222073291 @default.
- W3022207329 hasLocation W30222073292 @default.
- W3022207329 hasOpenAccess W3022207329 @default.
- W3022207329 hasPrimaryLocation W30222073291 @default.
- W3022207329 hasRelatedWork W1641042124 @default.
- W3022207329 hasRelatedWork W1967231335 @default.
- W3022207329 hasRelatedWork W1990804418 @default.
- W3022207329 hasRelatedWork W1993764875 @default.
- W3022207329 hasRelatedWork W2013243191 @default.
- W3022207329 hasRelatedWork W2051339581 @default.
- W3022207329 hasRelatedWork W2082860237 @default.
- W3022207329 hasRelatedWork W2117258802 @default.
- W3022207329 hasRelatedWork W2130076355 @default.
- W3022207329 hasRelatedWork W2151865869 @default.
- W3022207329 hasVolume "51" @default.
- W3022207329 isParatext "false" @default.
- W3022207329 isRetracted "false" @default.
- W3022207329 magId "3022207329" @default.
- W3022207329 workType "article" @default.