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- W3022250012 abstract "Abstract The biosynthesis pathways of bacterial glycoconjugate molecules, especially of those molecules that traffic across the cytoplasmic membrane and reside extracytoplasmically has biologically conserved features including the saccharides are formed as lipid-linked glycans anchored to cell membranes, the lipid anchors are polyisoprenoid phosphates, and the assembly reactions occur at both sides of the cell membrane, typically commencing on the cytosolic side and continuing at the opposite side of the membrane, for which the transmembrane movement of the lipid-linked saccharides is an obligatory step. After membrane translocation, additional reactions at the external side of the cell membrane are essential to complete the biosynthesis of bacterial glycoconjugates. One of these reactions involves the glycosyl transfer of the saccharide portion (a monosaccharide, an oligosaccharide, or a polysaccharide chain) of polyisoprenyl-linked substrates to the appropriate acceptor molecules. This chapter describes the main structural and topological properties of prototypic bacterial posttranslocation glycosyltransferases or “glycan ligases.”" @default.
- W3022250012 created "2020-05-13" @default.
- W3022250012 creator A5041019879 @default.
- W3022250012 date "2020-01-01" @default.
- W3022250012 modified "2023-10-14" @default.
- W3022250012 title "Glycan ligation reactions in the periplasmic space" @default.
- W3022250012 doi "https://doi.org/10.1016/b978-0-12-820954-7.00002-5" @default.
- W3022250012 hasPublicationYear "2020" @default.
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