FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3022332104> ?p ?o ?g. }

• W3022332104 endingPage "2858" @default.
• W3022332104 startingPage "2848" @default.
• W3022332104 abstract "Oral lichen planus (OLP) is a common chronic inflammatory autoimmune disease with unclear etiology. The aim of the present study was to identify the expression profiles of circulating exosomal miRNAs, which have been shown to be potent stimulators of inflammatory and immune responses, in OLP patients. Plasma exosomes were isolated from the patients and healthy individuals, and RAE scoring system was used to evaluate the severity of OLP. Differentially deregulated exosomal miRNAs associated with inflammatory response and autoimmunity in OLP were identified by miScript® miRNA PCR Array, and the results were confirmed by RT-PCR. The relationship between exosomal miRNAs and RAE scores was then analyzed, and bioinformatics analysis was used to predict the target genes and pathways of the differentially expressed exosomal miRNAs. Expression profiling showed that circulating exosomal miR-34a-5p and miR-130b-3p were upregulated, while miR-301b-3p was downregulated in OLP patients. Exosomal miR-34a-5p was positively correlated with the severity of OLP. Bioinformatics analysis revealed that the target genes of miR-34a-5p were mainly involved in regulation of gene expression, cell communication, signaling, and metabolic process, and modulated OLP progression through the PI3K/Akt signaling pathway. In conclusion, circulating exosomal miR-34a-5p could be a potential biomarker for evaluating the severity of OLP." @default.
• W3022332104 created "2020-05-13" @default.
• W3022332104 creator A5007876335 @default.
• W3022332104 creator A5017947172 @default.
• W3022332104 creator A5058476148 @default.
• W3022332104 date "2018-01-01" @default.
• W3022332104 modified "2023-09-23" @default.
• W3022332104 title "Differentially circulating exosomal microRNAs expression profiling in oral lichen planus." @default.
• W3022332104 cites W1500925570 @default.
• W3022332104 cites W1514821037 @default.
• W3022332104 cites W1523568809 @default.
• W3022332104 cites W1966940637 @default.
• W3022332104 cites W1977269216 @default.
• W3022332104 cites W1992217777 @default.
• W3022332104 cites W2018687481 @default.
• W3022332104 cites W2032735323 @default.
• W3022332104 cites W2033371906 @default.
• W3022332104 cites W2034591663 @default.
• W3022332104 cites W2036953459 @default.
• W3022332104 cites W2039975023 @default.
• W3022332104 cites W2047356483 @default.
• W3022332104 cites W2054037801 @default.
• W3022332104 cites W2058720888 @default.
• W3022332104 cites W2060088652 @default.
• W3022332104 cites W2071371341 @default.
• W3022332104 cites W2075503219 @default.
• W3022332104 cites W2079486550 @default.
• W3022332104 cites W2090525477 @default.
• W3022332104 cites W2091868933 @default.
• W3022332104 cites W2100771939 @default.
• W3022332104 cites W2128585463 @default.
• W3022332104 cites W2252600750 @default.
• W3022332104 cites W2263281129 @default.
• W3022332104 cites W2264513531 @default.
• W3022332104 cites W2270960316 @default.
• W3022332104 cites W2302350737 @default.
• W3022332104 cites W2327694191 @default.
• W3022332104 cites W2333374948 @default.
• W3022332104 cites W2344717814 @default.
• W3022332104 cites W2409180880 @default.
• W3022332104 cites W2418191755 @default.
• W3022332104 cites W2419237432 @default.
• W3022332104 cites W2468796126 @default.
• W3022332104 cites W2471585718 @default.
• W3022332104 cites W2513413220 @default.
• W3022332104 cites W2528709510 @default.
• W3022332104 cites W2534709643 @default.
• W3022332104 cites W2563481002 @default.
• W3022332104 cites W2564934753 @default.
• W3022332104 cites W2574266062 @default.
• W3022332104 cites W2588466467 @default.
• W3022332104 cites W2589694509 @default.
• W3022332104 cites W2604808360 @default.
• W3022332104 cites W2605377619 @default.
• W3022332104 cites W2610195036 @default.
• W3022332104 cites W2613983133 @default.
• W3022332104 cites W2735491497 @default.
• W3022332104 cites W3025075911 @default.
• W3022332104 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6176222" @default.
• W3022332104 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/30323871" @default.
• W3022332104 hasPublicationYear "2018" @default.
• W3022332104 type Work @default.
• W3022332104 sameAs 3022332104 @default.
• W3022332104 citedByCount "8" @default.
• W3022332104 countsByYear W30223321042019 @default.
• W3022332104 countsByYear W30223321042020 @default.
• W3022332104 countsByYear W30223321042022 @default.
• W3022332104 countsByYear W30223321042023 @default.
• W3022332104 crossrefType "journal-article" @default.
• W3022332104 hasAuthorship W3022332104A5007876335 @default.
• W3022332104 hasAuthorship W3022332104A5017947172 @default.
• W3022332104 hasAuthorship W3022332104A5058476148 @default.
• W3022332104 hasConcept C104317684 @default.
• W3022332104 hasConcept C127561419 @default.
• W3022332104 hasConcept C145059251 @default.
• W3022332104 hasConcept C150194340 @default.
• W3022332104 hasConcept C18431079 @default.
• W3022332104 hasConcept C203014093 @default.
• W3022332104 hasConcept C20518536 @default.
• W3022332104 hasConcept C2776201145 @default.
• W3022332104 hasConcept C2779018089 @default.
• W3022332104 hasConcept C2780130043 @default.
• W3022332104 hasConcept C2781197716 @default.
• W3022332104 hasConcept C2781261824 @default.
• W3022332104 hasConcept C502942594 @default.
• W3022332104 hasConcept C54355233 @default.
• W3022332104 hasConcept C71924100 @default.
• W3022332104 hasConcept C86803240 @default.
• W3022332104 hasConcept C8891405 @default.
• W3022332104 hasConceptScore W3022332104C104317684 @default.
• W3022332104 hasConceptScore W3022332104C127561419 @default.
• W3022332104 hasConceptScore W3022332104C145059251 @default.
• W3022332104 hasConceptScore W3022332104C150194340 @default.
• W3022332104 hasConceptScore W3022332104C18431079 @default.
• W3022332104 hasConceptScore W3022332104C203014093 @default.
• W3022332104 hasConceptScore W3022332104C20518536 @default.
• W3022332104 hasConceptScore W3022332104C2776201145 @default.
• W3022332104 hasConceptScore W3022332104C2779018089 @default.

• next