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- W3022350079 abstract "Pathogenic microorganism delays wound-healing process by causing infection. In recent years, researchers have developed various kinds of photo-active nanomaterials with enhanced antibacterial properties. This work focus on the preparation of graphene oxide and TiO2 nanocomposites (GO/TiO2) as a visible light-induced high efficiency antibacterial material. The hydrothermal method was used for the synthesis of GO/TiO2 nanocomposites at 180 oC for 3 h with different loading percentages of GO (10, 20, 30, 40 and 50 wt. %). The systematic characterization tools including X-ray diffraction analysis, FT-IR, UV-vis, Raman and TEM which were used to understand the physicochemical properties of the prepared GO/TiO2 nanocomposites. Furthermore, GO/TiO2 nanocomposites were used as photocatalytic active materials against wound infection-causing bacteria in the presence of visible light irradiation. The possible antibacterial mechanism under presence and absence of light were depicted. The antibacterial mechanism of the GO/TiO2 nanocomposite was investigated on wound infection-causing bacteria such as Staphylococcus aureus, Pseudomonas aeruginosa, Escherichia coli, and Enterococcus faecalis. The high hemocompatibility and the cellular biocompatibility of the nanocomposite aids in using it for wound-healing application. Overall, the results suggest that the GO/TiO2 nanocomposite could be developed as a photo-active nanomaterial against pathogenic microorganisms that are present in wound." @default.
- W3022350079 created "2020-05-13" @default.
- W3022350079 creator A5001560934 @default.
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- W3022350079 date "2020-05-23" @default.
- W3022350079 modified "2023-10-18" @default.
- W3022350079 title "Investigation on photo-induced mechanistic activity of GO/TiO<sub>2</sub> hybrid nanocomposite against wound pathogens" @default.
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- W3022350079 doi "https://doi.org/10.1080/15376516.2020.1765061" @default.
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