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- W3022357672 abstract "This chapter presents allergic disease. It also focuses on asthma. The history and examination are crucially important in making the diagnosis of hyperreactive airways. Investigation is not usually necessary unless the presentation is atypical or there is a poor response to appropriate therapy. Peak flow and exercise provocation are the only respiratory tests in common use. A personal or family history of eczema, chronic rhinitis, hay fever, or allergy to cheap jewelry (nickel) is present in 70% of asthmatic children, and others give a history of cough or wheeze at night or induced by exercise, cold, damp weather, emotion, or on exposure to specific materials. Examination may reveal eczema, allergic rhinitis, an overinflated chest with rhonchi, or Harrison's sulcus. Cell-mediated mechanisms, which are much less well understood, are more important in anything but extrinsic antigen-triggered asthma. A normal IgE does not exclude atopic asthma. Symptoms correlate better with eosinophilia than IgE because inflammation and nonspecific reactivity also contribute to airway obstruction." @default.
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- W3022357672 date "1990-01-01" @default.
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- W3022357672 title "Allergic disease" @default.
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- W3022357672 doi "https://doi.org/10.1016/b978-0-7236-0973-5.50018-6" @default.
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