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- W3022359849 abstract "The environmental toxicity of tetracycline antibiotics to aquatic organisms has attracted increasing attention. The adverse impacts of tetracycline antibiotics on ciliates should be detailed considering the significant roles of protozoa in the microfood web in the soils and other eco-systems. This study for the first time investigated the toxicity of two typical tetracycline antibiotics, tetracycline (TC) and tetracycline hydrochloride (HTC) on two primary model ciliates, Stentor coeruleus and Stylonychia lemnae. The concentrations for 50% of maximal effect (24h‒EC50) of TC and HTC to Stentor coeruleus were 94.4 mg/L and 8.39 mg/L, respectively. Correspondingly, the 24h‒EC50 values of TC and HTC to Stylonychia lemnae were 40.1 mg/L and 14.0 mg/L, respectively. The TC and HTC inhibited the growth rates, reduced the activities of antioxidant enzymes, and damaged the ultra-structures of the tested ciliate cells, with the latter having larger impacts than the former. Based on the experimental works reported herein, the two model protozoan species were proposed to be the toxicity indicators for tetracycline antibiotics, which could work as supplements with the other existing protocols, such as Brochydanio rerio (zebrafish), Limnodrilus (a worm), Chlorogonium elongatum (a green alga) also studied herein." @default.
- W3022359849 created "2020-05-13" @default.
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- W3022359849 date "2020-09-01" @default.
- W3022359849 modified "2023-10-16" @default.
- W3022359849 title "Toxicity of two tetracycline antibiotics on Stentor coeruleus and Stylonychia lemnae: Potential use as toxicity indicator" @default.
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- W3022359849 doi "https://doi.org/10.1016/j.chemosphere.2020.127011" @default.
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