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• W3022366206 abstract "We read the article by Abela et al. 1 Abela C. Hartmann C.E. De Leo A. et al. Toxic epidermal necrolysis (TEN): the Chelsea and Westminster hospital wound management algorithm. J Plast Reconstr Aesthet Surg. 2014 Aug; 67: 1026-1032 Abstract Full Text Full Text PDF PubMed Scopus (29) Google Scholar with much interest and they are to be congratulated for their proposed TEN wound management algorithm. This is in view of the fact that there is at present no international consensus for the management of TEN with regards to medical therapy or wound care. It is however generally agreed that management in a burn centre is indicated as TEN presents many treatment issues similar to that of a major superficial partial thickness burn; such as monitoring of the fluid - electrolyte balance, providing enteral nutrition, wound care and prevention/treatment of sepsis. We treat several cases of TEN per annum in the Helsinki Burn Centre in keeping with the annual UK incidence of 1–2 cases per million population (our centre serves the whole of Finland with a population of 5.4 million). Wound care forms a key part of the overall management of the patient with relief of pain and prevention of wound sepsis the main challenges. We take every patient to theatre for a gentle scrubdown, removal of any non-adherent ‘lysed’epidermis and cleansing of the wounds. This enables a thorough assessment of the extent of disease. We then apply the skin substitute Suprathel® (PolyMedics Innovations, Filderstadt, Germany) to the denuded areas. If there is any ocular involvement then an ophthalmologist is also able to assess and instigate treatment such as lysis of adhesions whilst the patient is anaesthetised. Toxic epidermal necrolysis (TEN): The Chelsea and Westminster Hospital wound management algorithmJournal of Plastic, Reconstructive & Aesthetic SurgeryVol. 67Issue 8PreviewToxic epidermal necrolysis syndrome (TEN) is a potentially catastrophic exfoliative muco-cutaneous disorder first described by Lyell in 1956. It represents the most extensive form of Steven–Johnson syndrome. TEN is defined varyingly around the globe, but in the United Kingdom the consensus opinion describes the process as involving >30% of the total body surface area. It can rapidly become more extensive and threatens life. The estimated annual incidence is approximately 1–2 cases per million population. Full-Text PDF" @default.
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• W3022366206 date "2015-02-01" @default.
• W3022366206 modified "2023-09-27" @default.
• W3022366206 title "Re: Toxic epidermal necrolysis (TEN): The Chelsea and Westminster hospital wound management algorithm" @default.
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• W3022366206 doi "https://doi.org/10.1016/j.bjps.2014.09.031" @default.
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