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- W3022386124 abstract "Publisher SummaryThe aging of a patient or any part or region of a patient may be regarded as the composite effect of aging on the cells. It is, however, unreasonable to anticipate that all cells age in unison. This chapter discusses the current theories of aging and the current data related to the age changes seen in the oral cavity. The aging of a person may be regarded as the composite effect of aging of cells. As a result, most of the theories as to the cause of aging center on cellular aging. The chapter discusses organ theories, neuro-endocrine system theories, and physiological theories. The organ theories are based on the contention that increments or decrements occur in organ functioning with increasing age. This theory contends that the immune system, brain, and neuro-endocrine system are the organs principally affected. The somatic mutation theory contends that the accumulation of a sufficient level of mutations in somatic cells will produce physiological decrements characteristic of aging. The program theory contends that the life-span of a cell or tissue is programmed into the genome. This theory assumes that initially well-ordered genetic programs become progressively disordered, resulting in the changes recognized as aging." @default.
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- W3022386124 date "1988-01-01" @default.
- W3022386124 modified "2023-09-26" @default.
- W3022386124 title "Age (gerontology)" @default.
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- W3022386124 doi "https://doi.org/10.1016/b978-0-7236-0818-9.50017-0" @default.
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