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• W302242562 startingPage "239" @default.
• W302242562 abstract "HOLTZMAN (1974, 1975) was the first to report that the pure opioid receptor antagonist, naloxone, significantly reduced food consumption in rats. At first these unexpected results were difficult to interpret. However, following the discovery of endogenous opioid peptides, these data could be explained in terms of the antagonism of endogenous opioid activity (SANGER 1981; MORLEY and LEVINE 1982; COOPER and SANGER 1984). The suppressant effects of naloxone and other opioid receptor antagonists on feeding behaviour were described initially using food-deprived rats and mice (e.g. HOLTZMAN 1974; ROGERS et al. 1978; MARGULES et al. 1978; BRANDS et al. 1979; BROWN and HOLTZMAN 1979). Naloxone also reduced free-feeding and drinking in rats (COOPER 1980), as well as eating induced by tail pinch (Lowy et al. 1980; MORLEY and LEVINE 1980), by 2-deoxY-D-glucose (SEWELL and JAWAHARLAL 1980), and by electrical stimulation of the brain (CARR and SIMON 1983)." @default.
• W302242562 created "2016-06-24" @default.
• W302242562 creator A5020739932 @default.
• W302242562 creator A5063167974 @default.
• W302242562 date "1993-01-01" @default.
• W302242562 modified "2023-10-06" @default.
• W302242562 title "Opioid Mechanisms in the Control of Food Consumption and Taste Preferences" @default.
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