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• W3022496095 abstract "The uses of sRNAs as new resources for functional studies and strain modifications are promising strategies in microorganisms. However, these crucial regulatory molecules have hardly been explored in industrially important solventogenic clostridia. Here, we identified sr8384 as a novel determinant sRNA controlling the cell growth of solventogenic Clostridium acetobutylicum . Based on a detailed functional analysis, we further reveal the pleiotropic function of sr8384 and its multiple direct and indirect crucial targets, which represents a valuable source for understanding and optimizing this anaerobe. Of note, manipulation of this sRNA achieves improved cell growth and solvent synthesis. Our findings provide a new perspective for future studies on regulatory sRNAs in clostridia." @default.
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• W3022496095 date "2020-06-17" @default.
• W3022496095 modified "2023-10-09" @default.
• W3022496095 title "The Small RNA sr8384 Is a Crucial Regulator of Cell Growth in Solventogenic Clostridia" @default.
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• W3022496095 doi "https://doi.org/10.1128/aem.00665-20" @default.
• W3022496095 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7301862" @default.
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• W3022496095 hasPublicationYear "2020" @default.
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