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- W3022630023 abstract "The world is facing one of the major outbreaks of viral infection of the modern history, however, as vaccine development workflow is still tedious and can not control the infection spreading, researchers are turning to passive immunization as a good and quick alternative to treat and contain the spreading. Within passive immunization domain, raising specific immunoglobulin (Ig)Y against acute respiratory tract infection has been developing for more than 20 years. Far from being an obsolete chapter we will revise the IgY‑technology as a new frontier for research and clinic. A wide range of IgY applications has been effectively confirmed in both human and animal health. The molecular particularities of IgY give them functional advantages recommending them as good candidates in this endeavor. Obtaining specific IgY is sustained by reliable and nature friendly methodology as an alternative for mammalian antibodies. The aria of application is continuously enlarging from bacterial and viral infections to tumor biology. Specific anti‑viral IgY were previously tested in several designs, thus its worth pointing out that in the actual COVID-19 pandemic context, respiratory infections need an enlarged arsenal of therapeutic approaches and clearly the roles of IgY should be exploited in depth." @default.
- W3022630023 created "2020-05-13" @default.
- W3022630023 creator A5018097997 @default.
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- W3022630023 creator A5043849185 @default.
- W3022630023 creator A5074046600 @default.
- W3022630023 creator A5077451508 @default.
- W3022630023 date "2020-04-30" @default.
- W3022630023 modified "2023-09-28" @default.
- W3022630023 title "IgY ‑ turning the page toward passive immunization in COVID-19 infection (Review)" @default.
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- W3022630023 doi "https://doi.org/10.3892/etm.2020.8704" @default.
- W3022630023 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7282020" @default.