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• W3022658261 abstract "The advancing average life expectancy of the population of the United States has resulted in more than 15 million people currently older than the age of 80 years (5.1 million older than the age of 85). 1 Avery 2nd, G.J. Ley S.J. Hill J.D. et al. Cardiac surgery in the octogenarian: Evaluation of risk, cost, and outcome. Ann Thorac Surg. 2001; 71: 591-596 Abstract Full Text Full Text PDF PubMed Scopus (137) Google Scholar Octogenarians will constitute 10% of the overall U.S. population by 2020. 2 U. S. Census BureauU.S. interim projections by age, sex, race, and Hispanic origins. U.S. Census Bureau, Washington, DC2004http://www.census.gov/ipc/www/usinterimproj Google Scholar Calcific aortic stenosis is common in this population. 3 Ferguson Jr, T.B. Hammill B.G. Peterson E.D. et al. A decade of change: Risk profiles and outcomes for isolated coronary artery bypass grafting procedures, 1990-1999—A report from the STS National Database Committee and the Duke Clinical Research Institute, Society of Thoracic Surgeons. Ann Thorac Surg. 2002; 73: 480-489 Abstract Full Text Full Text PDF PubMed Scopus (554) Google Scholar The only effective therapeutic option for symptomatic severe aortic stenosis is aortic valve replacement (AVR). Although the results of surgery have improved in this patient population during the last decade, several studies have identified predictors of hospital mortality, including renal failure, low ejection fraction, peripheral vascular disease, extensive ascending aortic calcification, and reoperative valve replacement. 4 Filsoufi F. Rahmanian P.B. Castillo J.G. et al. Excellent early and late outcomes of aortic valve replacement in people aged 80 and older. J Am Geriatr Soc. 2008; 56: 255-261 Crossref PubMed Scopus (60) Google Scholar In patients in whom standard surgical AVR is not recommended, transcatheter aortic valve implantation (TAVI) has recently become a viable therapeutic option. 5 Holmes Jr, D.R. Mack M.J. Transcatheter valve therapy: A professional society overview from the American College of Cardiology Foundation and the Society of Thoracic Surgeons. J Am Coll Cardiol. 2011; 58: 445-455 Abstract Full Text Full Text PDF PubMed Scopus (71) Google Scholar However, this technology is not yet freely available and is contraindicated in some patients, including those with bicuspid aortic valve and mobile atheroma in the ascending aorta. In these patients, apicoaortic conduit (AAC), otherwise called aortic valve bypass, remains a well-accepted alternative treatment. 6 Gammie J.S. Krowsoski L.S. Brown J.M. et al. Aortic valve bypass surgery: Midterm clinical outcomes in a high-risk aortic stenosis population. Circulation. 2008; 118: 1460-1466 Crossref PubMed Scopus (61) Google Scholar Furthermore, TAVI still remains under clinical investigation, with several unresolved issues such as the need for pacemakers, the occurrence of paravalvular leaks, and the incidence of periprocedural stroke. All of these complications are not generally associated with AAC. 6 Gammie J.S. Krowsoski L.S. Brown J.M. et al. Aortic valve bypass surgery: Midterm clinical outcomes in a high-risk aortic stenosis population. Circulation. 2008; 118: 1460-1466 Crossref PubMed Scopus (61) Google Scholar" @default.
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• W3022658261 date "2012-01-01" @default.
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• W3022658261 title "Apicoaortic Conduit" @default.
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