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• W3022674144 abstract "Tomato leaf curl Guangdong virus (ToLCGdV) is a begomovirus associated with a Tomato yellow leaf curl disease (TYLCD) epidemic in Guangdong province, China. Being the least conserved protein among geminivirus proteins, the function of C4 during ToLCGdV infection has not been elucidated. In this study, the infectious clones of ToLCGdV and a ToLCGdV mutant (ToLCGdVmC4) with disrupted C4 ORF were constructed. Although ToLCGdV and ToLCGdVmC4 could infect N. benthamiana and tomato plants, ToLCGdVmC4 elicited much milder symptoms compared with ToLCGdV. To further verify the role of C4 in viral pathogenesis, C4 was expressed in Nicotiana benthamiana from Potato virus X (PVX) vector. The results showed that ToLCGdV C4 enhanced the pathogenicity of PVX and induced more severe developmental abnormalities in plants compared with PVX alone or PVX-mC4. In addition, ToLCGdV C4 suppresses systemic gene silencing in the transgenic N. benthamiana line 16c, but not local gene silencing induced by sense GFP in wild-type N. benthamiana plants. Moreover, C4 suppresses transcriptional gene silencing (TGS) by reducing the DNA methylation level of 35S promoter in 16c-TGS N. benthamiana plants. Furthermore, C4 could also interact with the receptor-like kinase (RLK) BARELY ANY MERISTEM 1 (BAM1), suggesting that C4 may suppress gene silencing by interfering with the function of BAM1 in the cell-to-cell spread of RNAi. All these results suggest that C4 is a pathogenic determinant of ToLCGdV, and C4 may suppress post-transcriptional gene silencing (PTGS) by interacting with BAM1." @default.
• W3022674144 created "2020-05-13" @default.
• W3022674144 creator A5001586232 @default.
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• W3022674144 creator A5087264224 @default.
• W3022674144 creator A5091300676 @default.
• W3022674144 date "2020-05-05" @default.
• W3022674144 modified "2023-09-27" @default.
• W3022674144 title "C4, the Pathogenic Determinant of Tomato Leaf Curl Guangdong Virus, May Suppress Post-transcriptional Gene Silencing by Interacting With BAM1 Protein" @default.
• W3022674144 cites W12154551 @default.
• W3022674144 cites W1492087182 @default.
• W3022674144 cites W1504404542 @default.
• W3022674144 cites W1546321334 @default.
• W3022674144 cites W1631037284 @default.
• W3022674144 cites W1937173755 @default.
• W3022674144 cites W1966545925 @default.
• W3022674144 cites W1967835839 @default.
• W3022674144 cites W1995500998 @default.
• W3022674144 cites W1996645904 @default.
• W3022674144 cites W1999595927 @default.
• W3022674144 cites W2003417565 @default.
• W3022674144 cites W2007164847 @default.
• W3022674144 cites W2012622394 @default.
• W3022674144 cites W2017296791 @default.
• W3022674144 cites W2018731279 @default.
• W3022674144 cites W2025785494 @default.
• W3022674144 cites W2031028828 @default.
• W3022674144 cites W2034388690 @default.
• W3022674144 cites W2037268784 @default.
• W3022674144 cites W2039240110 @default.
• W3022674144 cites W2040509450 @default.
• W3022674144 cites W2055805446 @default.
• W3022674144 cites W2062196558 @default.
• W3022674144 cites W2062769593 @default.
• W3022674144 cites W2064123476 @default.
• W3022674144 cites W2065977014 @default.
• W3022674144 cites W2068730569 @default.
• W3022674144 cites W2072424699 @default.
• W3022674144 cites W2074983262 @default.
• W3022674144 cites W2075696990 @default.
• W3022674144 cites W2080362571 @default.
• W3022674144 cites W2080655727 @default.
• W3022674144 cites W2088926313 @default.
• W3022674144 cites W2089711178 @default.
• W3022674144 cites W2090722696 @default.
• W3022674144 cites W2090820399 @default.
• W3022674144 cites W2094074766 @default.
• W3022674144 cites W2099655440 @default.
• W3022674144 cites W2105144091 @default.
• W3022674144 cites W2109458502 @default.
• W3022674144 cites W2110259827 @default.
• W3022674144 cites W2111222063 @default.
• W3022674144 cites W2113588666 @default.
• W3022674144 cites W2117984526 @default.
• W3022674144 cites W2118055578 @default.
• W3022674144 cites W2123058210 @default.
• W3022674144 cites W2126667640 @default.
• W3022674144 cites W2151885957 @default.
• W3022674144 cites W2152218791 @default.
• W3022674144 cites W2155041799 @default.
• W3022674144 cites W2157514051 @default.
• W3022674144 cites W2157995729 @default.
• W3022674144 cites W2161114129 @default.
• W3022674144 cites W2164200689 @default.
• W3022674144 cites W2166887957 @default.
• W3022674144 cites W2167998323 @default.
• W3022674144 cites W2168441066 @default.
• W3022674144 cites W2170117443 @default.
• W3022674144 cites W2193019252 @default.
• W3022674144 cites W2311203695 @default.
• W3022674144 cites W2514170006 @default.
• W3022674144 cites W2595220198 @default.
• W3022674144 cites W2604396651 @default.
• W3022674144 cites W2757884343 @default.
• W3022674144 cites W2782266294 @default.
• W3022674144 cites W2785077527 @default.
• W3022674144 cites W2793138436 @default.
• W3022674144 cites W2794165178 @default.
• W3022674144 cites W2809669341 @default.
• W3022674144 cites W2885764280 @default.
• W3022674144 cites W2889451554 @default.
• W3022674144 cites W2898527413 @default.
• W3022674144 cites W2913677663 @default.
• W3022674144 cites W2938793257 @default.
• W3022674144 cites W2952192424 @default.
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• W3022674144 doi "https://doi.org/10.3389/fmicb.2020.00851" @default.
• W3022674144 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7215500" @default.
• W3022674144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32431688" @default.
• W3022674144 hasPublicationYear "2020" @default.
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