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• W3022680399 endingPage "112390" @default.
• W3022680399 startingPage "112390" @default.
• W3022680399 abstract "The mycobacterial membrane protein Large 3 (MmpL3) is an inner membrane protein that transports trehalose-monomycolates, precursors for trehalose-dimycolates and mycolic acids that make up essential components of the mycobacterial outer membrane. Inhibition of MmpL3 weakens the mycobacterial cell wall and ultimately results in cell death in both in vitro and in vivo infection models. This highlights the therapeutic potential of MmpL3 as a drug target. High-throughput whole-cell screening along with whole genome sequencing of resistant mutants has identified numerous classes of compounds that can be classified as MmpL3 inhibitors. In this review, we provide insights into the current development of various MmpL3 inhibitors and discuss the potential challenges in this area." @default.
• W3022680399 created "2020-05-13" @default.
• W3022680399 creator A5022625504 @default.
• W3022680399 creator A5045350828 @default.
• W3022680399 creator A5048049913 @default.
• W3022680399 creator A5090932473 @default.
• W3022680399 date "2020-08-01" @default.
• W3022680399 modified "2023-09-26" @default.
• W3022680399 title "MmpL3 inhibitors as antituberculosis drugs" @default.
• W3022680399 cites W1540126244 @default.
• W3022680399 cites W1836818673 @default.
• W3022680399 cites W1900494116 @default.
• W3022680399 cites W1963981929 @default.
• W3022680399 cites W1964663856 @default.
• W3022680399 cites W1964734437 @default.
• W3022680399 cites W1966719805 @default.
• W3022680399 cites W1969349373 @default.
• W3022680399 cites W1971129422 @default.
• W3022680399 cites W1971898202 @default.
• W3022680399 cites W1977747017 @default.
• W3022680399 cites W1978907472 @default.
• W3022680399 cites W1980932683 @default.
• W3022680399 cites W1984864669 @default.
• W3022680399 cites W1986288809 @default.
• W3022680399 cites W1987669663 @default.
• W3022680399 cites W1989425514 @default.
• W3022680399 cites W1995574940 @default.
• W3022680399 cites W1996907187 @default.
• W3022680399 cites W2005036750 @default.
• W3022680399 cites W2023817396 @default.
• W3022680399 cites W2029076581 @default.
• W3022680399 cites W2032448480 @default.
• W3022680399 cites W2032982721 @default.
• W3022680399 cites W2034080889 @default.
• W3022680399 cites W2035787643 @default.
• W3022680399 cites W2048209077 @default.
• W3022680399 cites W2052284685 @default.
• W3022680399 cites W2053534534 @default.
• W3022680399 cites W2053717624 @default.
• W3022680399 cites W2054495447 @default.
• W3022680399 cites W2059977407 @default.
• W3022680399 cites W2065903108 @default.
• W3022680399 cites W2069127863 @default.
• W3022680399 cites W2070190311 @default.
• W3022680399 cites W2071932302 @default.
• W3022680399 cites W2078486393 @default.
• W3022680399 cites W2081977228 @default.
• W3022680399 cites W2089465091 @default.
• W3022680399 cites W2098146193 @default.
• W3022680399 cites W2099377706 @default.
• W3022680399 cites W2103620979 @default.
• W3022680399 cites W2105716423 @default.
• W3022680399 cites W2110373384 @default.
• W3022680399 cites W2113951828 @default.
• W3022680399 cites W2124757426 @default.
• W3022680399 cites W2130990567 @default.
• W3022680399 cites W2134822873 @default.
• W3022680399 cites W2139012536 @default.
• W3022680399 cites W2143144919 @default.
• W3022680399 cites W2149415226 @default.
• W3022680399 cites W2152378366 @default.
• W3022680399 cites W2155375392 @default.
• W3022680399 cites W2158023121 @default.
• W3022680399 cites W2158658436 @default.
• W3022680399 cites W2164718888 @default.
• W3022680399 cites W2165243436 @default.
• W3022680399 cites W2165898417 @default.
• W3022680399 cites W2175184680 @default.
• W3022680399 cites W2177577861 @default.
• W3022680399 cites W2342849480 @default.
• W3022680399 cites W2377866320 @default.
• W3022680399 cites W2407396248 @default.
• W3022680399 cites W2410717087 @default.
• W3022680399 cites W2420893966 @default.
• W3022680399 cites W2460787949 @default.
• W3022680399 cites W2518224721 @default.
• W3022680399 cites W2581560932 @default.
• W3022680399 cites W2593911600 @default.
• W3022680399 cites W2612186309 @default.
• W3022680399 cites W2735401266 @default.
• W3022680399 cites W2753528813 @default.
• W3022680399 cites W2776361382 @default.
• W3022680399 cites W2791375569 @default.
• W3022680399 cites W2798069536 @default.
• W3022680399 cites W2810243982 @default.
• W3022680399 cites W2888707043 @default.
• W3022680399 cites W2901406400 @default.
• W3022680399 cites W2913841228 @default.
• W3022680399 cites W2913867994 @default.
• W3022680399 cites W2921257501 @default.
• W3022680399 cites W2947689936 @default.
• W3022680399 cites W2953309325 @default.
• W3022680399 cites W2963187154 @default.
• W3022680399 cites W2965834850 @default.
• W3022680399 cites W2973815244 @default.
• W3022680399 cites W2995070755 @default.
• W3022680399 doi "https://doi.org/10.1016/j.ejmech.2020.112390" @default.
• W3022680399 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32447196" @default.

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