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• W3022738324 endingPage "101097" @default.
• W3022738324 startingPage "101097" @default.
• W3022738324 abstract "Abstract Amyloid β-protein, a polypeptide, is known as the reason of neuronal death and is widely recognized as a biomarker of Alzheimer's disease. In this study, a simple and rapid electrochemical biosensor based on delaminated titanium carbide MXene (d-Ti3C2TX MXene) and multi-walled carbon nanotubes (MWCNTs) composite including molecularly imprinted polymers (MIPs) was formed for amyloid-β having 42-amino-acid-peptide (Aβ42) protein sensing. After d-Ti3C2TX/MWCNTs composite was prepared by mixing the colloidal solution of d-Ti3C2TX MXene with MWCNTs (mass ratio 3:1), some analytic methods such as x-ray diffraction (XRD), x-ray photoelectron spectroscopy (XPS), scanning electron microscopy (SEM), UV/Vis spectroscopy, atomic force microscopy (AFM), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS) were performed for characterizations of d-Ti3C2TX MXene, MWCNTs and d-Ti3C2TX/MWCNTs composite. Later, Aβ42 imprinted d-Ti3C2TX/MWCNTs/GCE was prepared in a mixture including 100.0 mM pyrrole (monomer) containing 25.0 mM Aβ42 (template) in phosphate buffer (0.1 M, pH 7.5) by CV method for 25 cycles. Aβ42 imprinted electrode showed a linear range of 1.0 fg mL−1 - 100.0 fg mL-1 and detection limit (LOD) of 0.3 fg mL-1 were obtained. Aβ42 imprinted electrode was examined in terms of stability, repeatability, reproducibility and reusability. Finally, Aβ42 imprinted biosensor was applied to plasma samples for Aβ42 analysis." @default.
• W3022738324 created "2020-05-13" @default.
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• W3022738324 date "2020-06-01" @default.
• W3022738324 modified "2023-10-14" @default.
• W3022738324 title "Electrochemical detection of amyloid-β protein by delaminated titanium carbide MXene/multi-walled carbon nanotubes composite with molecularly imprinted polymer" @default.
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• W3022738324 doi "https://doi.org/10.1016/j.mtcomm.2020.101097" @default.
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