FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3022757718> ?p ?o ?g. }

• W3022757718 abstract "This review summarizes the state of the current literature relating to the associations of lung disease and adipokines (proteins produced by adipose tissue) in humans. The mechanistic basis for these associations in humans is not established, although a possible role for adipokines has been invoked. Leptin, a pro-inflammatory adipokine, and adiponectin, an anti-inflammatory adipokine, are causally associated with asthma in mice. Although human studies are currently inconclusive, high-serum leptin and low-serum adiponectin concentrations predict asthma, independent of obesity, in select population groups, such as premenopausal women in the United States. In contradistinction, low-serum leptin and high-serum adiponectin concentrations are associated with stable COPD, although these associations are likely confounded by fat mass. Interestingly, leptin may promote systemic and airway inflammation in stable COPD patients. On the other hand, COPD may upregulate systemic and lung adiponectin expression. The precise mechanism and significance of the associations between these adipokines and lung disease at the current stage are confusing and frankly paradoxical in places. It is now known that adipose tissue is not an inert organ simply for energy storage, but regulates systemic inflammation via a variety of secreted proteins (called adipokines). While the associations of obesity and adipokines with cardiovascular, endocrine, and rheumatological diseases are well described, the respiratory effects of obesity and adipokines are less well known. This review will focus on the effect of obesity and adipokines on asthma and chronic obstructive pulmonary disease (COPD) in humans. This area of research needs additional study that may open up novel therapeutic strategies for these lung diseases." @default.
• W3022757718 created "2020-05-13" @default.
• W3022757718 creator A5052783130 @default.
• W3022757718 creator A5058427422 @default.
• W3022757718 creator A5060399178 @default.
• W3022757718 creator A5068519156 @default.
• W3022757718 creator A5078087571 @default.
• W3022757718 date "2019-10-01" @default.
• W3022757718 modified "2023-09-27" @default.
• W3022757718 title "Role of adipokines in obstructive airway disease and diabetes mellitus" @default.
• W3022757718 cites W1485601868 @default.
• W3022757718 cites W1497019223 @default.
• W3022757718 cites W1551216731 @default.
• W3022757718 cites W1569539243 @default.
• W3022757718 cites W1584201247 @default.
• W3022757718 cites W1675830194 @default.
• W3022757718 cites W1845204874 @default.
• W3022757718 cites W1966652886 @default.
• W3022757718 cites W1968294487 @default.
• W3022757718 cites W1969403095 @default.
• W3022757718 cites W1972435690 @default.
• W3022757718 cites W1973228855 @default.
• W3022757718 cites W1977301749 @default.
• W3022757718 cites W1981261500 @default.
• W3022757718 cites W1990900950 @default.
• W3022757718 cites W1993208499 @default.
• W3022757718 cites W1996623626 @default.
• W3022757718 cites W1999178617 @default.
• W3022757718 cites W1999865009 @default.
• W3022757718 cites W2001951292 @default.
• W3022757718 cites W2008869160 @default.
• W3022757718 cites W2009660633 @default.
• W3022757718 cites W2012652877 @default.
• W3022757718 cites W2014769342 @default.
• W3022757718 cites W2025846514 @default.
• W3022757718 cites W2039845757 @default.
• W3022757718 cites W2042905891 @default.
• W3022757718 cites W2046675462 @default.
• W3022757718 cites W2058545695 @default.
• W3022757718 cites W2058898506 @default.
• W3022757718 cites W2062570379 @default.
• W3022757718 cites W2064119981 @default.
• W3022757718 cites W2065284668 @default.
• W3022757718 cites W2077799959 @default.
• W3022757718 cites W2083066110 @default.
• W3022757718 cites W2094016960 @default.
• W3022757718 cites W2094116654 @default.
• W3022757718 cites W2097066928 @default.
• W3022757718 cites W2099692602 @default.
• W3022757718 cites W2100277531 @default.
• W3022757718 cites W2100352028 @default.
• W3022757718 cites W2101921785 @default.
• W3022757718 cites W2106060576 @default.
• W3022757718 cites W2107645694 @default.
• W3022757718 cites W2109849857 @default.
• W3022757718 cites W2110378267 @default.
• W3022757718 cites W2113260956 @default.
• W3022757718 cites W2130064617 @default.
• W3022757718 cites W2130783110 @default.
• W3022757718 cites W2132919605 @default.
• W3022757718 cites W2132921286 @default.
• W3022757718 cites W2134767986 @default.
• W3022757718 cites W2135715979 @default.
• W3022757718 cites W2154353013 @default.
• W3022757718 cites W2154502881 @default.
• W3022757718 cites W2155332078 @default.
• W3022757718 cites W2156248782 @default.
• W3022757718 cites W2166687728 @default.
• W3022757718 cites W2169799551 @default.
• W3022757718 doi "https://doi.org/10.21276/ijrdpl.2278-0238.2019.8(4).13-17" @default.
• W3022757718 hasPublicationYear "2019" @default.
• W3022757718 type Work @default.
• W3022757718 sameAs 3022757718 @default.
• W3022757718 citedByCount "0" @default.
• W3022757718 crossrefType "journal-article" @default.
• W3022757718 hasAuthorship W3022757718A5052783130 @default.
• W3022757718 hasAuthorship W3022757718A5058427422 @default.
• W3022757718 hasAuthorship W3022757718A5060399178 @default.
• W3022757718 hasAuthorship W3022757718A5068519156 @default.
• W3022757718 hasAuthorship W3022757718A5078087571 @default.
• W3022757718 hasConcept C126322002 @default.
• W3022757718 hasConcept C134018914 @default.
• W3022757718 hasConcept C171089720 @default.
• W3022757718 hasConcept C194832188 @default.
• W3022757718 hasConcept C203014093 @default.
• W3022757718 hasConcept C2776042228 @default.
• W3022757718 hasConcept C2776780178 @default.
• W3022757718 hasConcept C2776782570 @default.
• W3022757718 hasConcept C2776914184 @default.
• W3022757718 hasConcept C2777391703 @default.
• W3022757718 hasConcept C2780578515 @default.
• W3022757718 hasConcept C2780613262 @default.
• W3022757718 hasConcept C2908647359 @default.
• W3022757718 hasConcept C511355011 @default.
• W3022757718 hasConcept C555293320 @default.
• W3022757718 hasConcept C71924100 @default.
• W3022757718 hasConcept C99454951 @default.
• W3022757718 hasConceptScore W3022757718C126322002 @default.
• W3022757718 hasConceptScore W3022757718C134018914 @default.
• W3022757718 hasConceptScore W3022757718C171089720 @default.

• next