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- W3022787309 abstract "To develop a computational tomography (CT) scanning protocol for the artifact-free imaging of a novel, intracavitary brachytherapy (ICBT) cervical applicator, in vivo. This protocol will exploit the rotating / translatable colpostat shield that is the characteristic feature of the prototype, high-dose-rate (HDR) ICBT applicator. A prototype cervical ICBT applicator was designed and constructed to feature a tungsten shield that rotates as well as translates along the long axis of the colpostat. The prototype was designed so that (a) its external dimensions are nearly equivalent to the clinical Fletcher-Williamson HDR ICBT applicator and (b) compatible with current Ir-192 remote after-loading technology. These features will facilitate an easier transition into a clinical setting. To acquire images, a “step-and-shoot” methodology was implemented. After inserting the prototype applicator into a plastic-water phantom and positioning the shield in its most proximal orientation, scout images were acquired with a GE Lightspeed CT scanner utilized for therapy simulations. From the scout images, one can determine the midpoint of the colpostat after insertion into patient. Utilizing a technique of 120keV and 200mA (derived from metallic implant CT protocols), an axial scan is taken inferiorly to the midpoint of the colpostat at which time the scanner is paused and the shield is translated remotely to its most distal position. The remaining slices are then taken as the scan is completed. This protocol was tested with the colpostat’s long-axis parallel to the couch as a “proof of principle” exercise as well as its long-axis oriented so that it made a 50 degree angle w.r.t. the couch; a clinically-applicable position. For the clinically-applicable orientation, the tilt of the scanner bore was utilized to minimize the relative angle between the applicator shield and primary direction of the imaging radiation. Utilizing this “step-and-shoot” method, CT image sets of the prototype applicator were acquired that did not contain the anatomy-blurring artifacts that are common to equivalent imaging of current LDR/HDR technologies. The results were true for both applicator shield orientations examined. A protocol has been developed for use in conjunction with a prototype ICBT cervical applicator, which features a remotely adjustable tungsten shield, which allows for the acquisition of CT images that are free from anatomy-blurring artifacts that are common to currently utilized HDR ICBT applicators." @default.
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- W3022787309 date "2006-11-01" @default.
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- W3022787309 doi "https://doi.org/10.1016/j.ijrobp.2006.07.1288" @default.
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