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• W3022823009 endingPage "143" @default.
• W3022823009 startingPage "119" @default.
• W3022823009 abstract "Regulation of the elongation phase of transcription by RNA polymerase II (Pol II) is utilized extensively to generate the pattern of mRNAs needed to specify cell types and to respond to environmental changes. After Pol II initiates, negative elongation factors cause it to pause in a promoter proximal position. These polymerases are poised to respond to the positive transcription elongation factor P-TEFb, and then enter productive elongation only under the appropriate set of signals to generate full-length properly processed mRNAs. Recent global analyses of Pol II and elongation factors, mechanisms that regulate P-TEFb involving the 7SK small nuclear ribonucleoprotein (snRNP), factors that control both the negative and positive elongation properties of Pol II, and the mRNA processing events that are coupled with elongation are discussed." @default.
• W3022823009 created "2020-05-13" @default.
• W3022823009 creator A5036097149 @default.
• W3022823009 creator A5038043249 @default.
• W3022823009 creator A5074762963 @default.
• W3022823009 date "2012-07-07" @default.
• W3022823009 modified "2023-10-16" @default.
• W3022823009 title "RNA Polymerase II Elongation Control" @default.
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