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- W3022876625 abstract "Introduction The 2017 European Association of the Study of Liver (EASL) Guidelines on management of Chronic Hepatitis B provided an update on monitoring of HBV patients. In E-Antigen negative patients, there is now clear guidance on the frequency of testing of Hepatitis B DNA, ALT, and non-invasive markers of liver fibrosis i.e. Fibroscan. Introduction of Quantitative Hepatitis B Surface Antigen(qHBsAg), can significantly reduce frequency of testing and follow-up. By introducing quantative Hepatitis B surface antigen we aim to to reduce unnecessary labarotory tests, and clinic visits thereby improving the patient experience and reducing costs. In addition, by introducing a local guideline we aim to follow best clinical practice Methods At the Whittington Hospital, we have 336 Chronic Hepatitis B patients in our service, of which 311 are E-antigen negative. 250 of these patients are under the age of 50. Two components of this audit/QIP. 1. A retrospective audit, of 10 patients, comparing current practice against the new EASL guidelines, to determine how many ALT and HBV DNA tests have been historically performed 2. Modelling of our cohort of patients over the next 6 years to predict future cost savings following introduction of 2017 EASL guideline recommendations. Costs of the relevant tests(HBV DNA, ALT, quantitative HbSAg and Fibroscan) were obtained from microbiology, biochemistry and finance department respectively. Results Our audit revealed we were performing too many HBV DNA tests. We performed 35 HBV DNA tests, as opposed to 5–11 HBV DNA tests, as per latest EASL guidelines. An ALT costs £1. A Fibroscan costs £44. A HBV DNA costs £65 and a Quantitative Surface Antigen costs £14. Using the EASL guidelines will significantly reduce the number of HBV DNA tests performed. This is beneficial for both the patient and will reduce costs to the trusts from unnecessary laboratory tests. In addition, by following the algorithm below, for patients with a qHBsAg Conclusions Implementation of the EASL guidelines would reduce the frequency of blood tests needed as well as the frequency of clinic follow ups. This is therefore much more beneficial to the patient. In addition, this would produce a cost saving to the trust estimated to be £100 per patient over a 6 year period for this cohort of patients" @default.
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- W3022876625 date "2018-06-01" @default.
- W3022876625 modified "2023-09-24" @default.
- W3022876625 title "PTU-136 Improving care for patients with chronic hepatitis B(HBV)" @default.
- W3022876625 doi "https://doi.org/10.1136/gutjnl-2018-bsgabstracts.514" @default.
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