FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W3022909442> ?p ?o ?g. }

• W3022909442 endingPage "3447" @default.
• W3022909442 startingPage "3437" @default.
• W3022909442 abstract "Abstract Aims The EUropean Comparative Effectiveness Research to Assess the Use of Primary ProphylacTic Implantable Cardioverter-Defibrillators (EU-CERT-ICD), a prospective investigator-initiated, controlled cohort study, was conducted in 44 centres and 15 European countries. It aimed to assess current clinical effectiveness of primary prevention ICD therapy. Methods and results We recruited 2327 patients with ischaemic cardiomyopathy (ICM) or dilated cardiomyopathy (DCM) and guideline indications for prophylactic ICD implantation. Primary endpoint was all-cause mortality. Clinical characteristics, medications, resting, and 12-lead Holter electrocardiograms (ECGs) were documented at enrolment baseline. Baseline and follow-up (FU) data from 2247 patients were analysable, 1516 patients before first ICD implantation (ICD group) and 731 patients without ICD serving as controls. Multivariable models and propensity scoring for adjustment were used to compare the two groups for mortality. During mean FU of 2.4 ± 1.1 years, 342 deaths occurred (6.3%/years annualized mortality, 5.6%/years in the ICD group vs. 9.2%/years in controls), favouring ICD treatment [unadjusted hazard ratio (HR) 0.682, 95% confidence interval (CI) 0.537–0.865, P = 0.0016]. Multivariable mortality predictors included age, left ventricular ejection fraction (LVEF), New York Heart Association class &lt;III, and chronic obstructive pulmonary disease. Adjusted mortality associated with ICD vs. control was 27% lower (HR 0.731, 95% CI 0.569–0.938, P = 0.0140). Subgroup analyses indicated no ICD benefit in diabetics (adjusted HR = 0.945, P = 0.7797, P for interaction = 0.0887) or those aged ≥75 years (adjusted HR 1.063, P = 0.8206, P for interaction = 0.0902). Conclusion In contemporary ICM/DCM patients (LVEF ≤35%, narrow QRS), primary prophylactic ICD treatment was associated with a 27% lower mortality after adjustment. There appear to be patients with less survival advantage, such as older patients or diabetics." @default.
• W3022909442 created "2020-05-13" @default.
• W3022909442 creator A5004362368 @default.
• W3022909442 creator A5005101797 @default.
• W3022909442 creator A5009342921 @default.
• W3022909442 creator A5009525051 @default.
• W3022909442 creator A5014828271 @default.
• W3022909442 creator A5017231528 @default.
• W3022909442 creator A5032319734 @default.
• W3022909442 creator A5032413649 @default.
• W3022909442 creator A5035866982 @default.
• W3022909442 creator A5049057788 @default.
• W3022909442 creator A5051676339 @default.
• W3022909442 creator A5056983761 @default.
• W3022909442 creator A5057325416 @default.
• W3022909442 creator A5063449841 @default.
• W3022909442 creator A5065123417 @default.
• W3022909442 creator A5068858051 @default.
• W3022909442 creator A5072773047 @default.
• W3022909442 creator A5074936599 @default.
• W3022909442 creator A5075724292 @default.
• W3022909442 creator A5075763660 @default.
• W3022909442 creator A5075962823 @default.
• W3022909442 creator A5080874217 @default.
• W3022909442 creator A5086398259 @default.
• W3022909442 creator A5086692319 @default.
• W3022909442 creator A5087433482 @default.
• W3022909442 date "2020-05-06" @default.
• W3022909442 modified "2023-10-12" @default.
• W3022909442 title "Clinical effectiveness of primary prevention implantable cardioverter-defibrillators: results of the EU-CERT-ICD controlled multicentre cohort study" @default.
• W3022909442 cites W1891676651 @default.
• W3022909442 cites W1967675646 @default.
• W3022909442 cites W1988262403 @default.
• W3022909442 cites W1999039355 @default.
• W3022909442 cites W1999130652 @default.
• W3022909442 cites W2003166545 @default.
• W3022909442 cites W2004909941 @default.
• W3022909442 cites W2012574332 @default.
• W3022909442 cites W2014477579 @default.
• W3022909442 cites W2035655846 @default.
• W3022909442 cites W2065712665 @default.
• W3022909442 cites W2068188321 @default.
• W3022909442 cites W2075175982 @default.
• W3022909442 cites W2095240637 @default.
• W3022909442 cites W2103679597 @default.
• W3022909442 cites W2108062940 @default.
• W3022909442 cites W2111412070 @default.
• W3022909442 cites W2118214230 @default.
• W3022909442 cites W2173456655 @default.
• W3022909442 cites W2266559694 @default.
• W3022909442 cites W2491324736 @default.
• W3022909442 cites W2518530324 @default.
• W3022909442 cites W2575790444 @default.
• W3022909442 cites W2599761051 @default.
• W3022909442 cites W2604329964 @default.
• W3022909442 cites W2606348638 @default.
• W3022909442 cites W2617814107 @default.
• W3022909442 cites W2624334115 @default.
• W3022909442 cites W2731248388 @default.
• W3022909442 cites W2742996681 @default.
• W3022909442 cites W2752674813 @default.
• W3022909442 cites W2804625362 @default.
• W3022909442 cites W2810823376 @default.
• W3022909442 cites W2898042900 @default.
• W3022909442 cites W2970042290 @default.
• W3022909442 cites W2982190194 @default.
• W3022909442 doi "https://doi.org/10.1093/eurheartj/ehaa226" @default.
• W3022909442 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7550196" @default.
• W3022909442 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32372094" @default.
• W3022909442 hasPublicationYear "2020" @default.
• W3022909442 type Work @default.
• W3022909442 sameAs 3022909442 @default.
• W3022909442 citedByCount "67" @default.
• W3022909442 countsByYear W30229094422020 @default.
• W3022909442 countsByYear W30229094422021 @default.
• W3022909442 countsByYear W30229094422022 @default.
• W3022909442 countsByYear W30229094422023 @default.
• W3022909442 crossrefType "journal-article" @default.
• W3022909442 hasAuthorship W3022909442A5004362368 @default.
• W3022909442 hasAuthorship W3022909442A5005101797 @default.
• W3022909442 hasAuthorship W3022909442A5009342921 @default.
• W3022909442 hasAuthorship W3022909442A5009525051 @default.
• W3022909442 hasAuthorship W3022909442A5014828271 @default.
• W3022909442 hasAuthorship W3022909442A5017231528 @default.
• W3022909442 hasAuthorship W3022909442A5032319734 @default.
• W3022909442 hasAuthorship W3022909442A5032413649 @default.
• W3022909442 hasAuthorship W3022909442A5035866982 @default.
• W3022909442 hasAuthorship W3022909442A5049057788 @default.
• W3022909442 hasAuthorship W3022909442A5051676339 @default.
• W3022909442 hasAuthorship W3022909442A5056983761 @default.
• W3022909442 hasAuthorship W3022909442A5057325416 @default.
• W3022909442 hasAuthorship W3022909442A5063449841 @default.
• W3022909442 hasAuthorship W3022909442A5065123417 @default.
• W3022909442 hasAuthorship W3022909442A5068858051 @default.
• W3022909442 hasAuthorship W3022909442A5072773047 @default.
• W3022909442 hasAuthorship W3022909442A5074936599 @default.
• W3022909442 hasAuthorship W3022909442A5075724292 @default.
• W3022909442 hasAuthorship W3022909442A5075763660 @default.

• next