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- W3022985747 abstract "Abstract Background RNA editing is a widespread co-/post-transcriptional mechanism that alters primary RNA sequences through the modification of specific nucleotides and it can increase both the transcriptome and proteome diversity. The automatic detection of RNA-editing from RNA-seq data is computational intensive and limited to small data sets, thus preventing a reliable genome-wide characterisation of such process. Results In this work we introduce HPC-REDItools, an upgraded tool for accurate RNA-editing events discovery from large dataset repositories. Availability: https://github.com/BioinfoUNIBA/REDItools2 . Conclusions HPC-REDItools is dramatically faster than the previous version, REDItools, enabling big-data analysis by means of a MPI-based implementation and scaling almost linearly with the number of available cores." @default.
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- W3022985747 date "2020-04-30" @default.
- W3022985747 modified "2023-10-16" @default.
- W3022985747 title "HPC-REDItools: a Novel HPC-aware Tool for Improved Large Scale RNA-editing Analysis" @default.
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- W3022985747 doi "https://doi.org/10.1101/2020.04.30.069732" @default.
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