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• W3022996820 abstract "You have accessJournal of UrologySexual Function/Dysfunction: Evaluation II (MP78)1 Apr 2020MP78-13 SERUM TESTOSTERONE LEVEL RISES DRASTICALLY AT THE MOMENT OF EJACULATION Yoshitomo Kobori*, Akiyoshi Osaka, Hisamitsu Ide, Hiroshi Okada, Gaku Arai, Tadahiko Tokumoto, Kiyoshi Setoguchi, Yoji Hyodo, Akinori Nakayama, Yasuyuki Inoue, Yuka Yasuda, and Shigehiro Soh Yoshitomo Kobori*Yoshitomo Kobori* More articles by this author , Akiyoshi OsakaAkiyoshi Osaka More articles by this author , Hisamitsu IdeHisamitsu Ide More articles by this author , Hiroshi OkadaHiroshi Okada More articles by this author , Gaku AraiGaku Arai More articles by this author , Tadahiko TokumotoTadahiko Tokumoto More articles by this author , Kiyoshi SetoguchiKiyoshi Setoguchi More articles by this author , Yoji HyodoYoji Hyodo More articles by this author , Akinori NakayamaAkinori Nakayama More articles by this author , Yasuyuki InoueYasuyuki Inoue More articles by this author , Yuka YasudaYuka Yasuda More articles by this author , and Shigehiro SohShigehiro Soh More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000964.013AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Testosterone is the major sex hormone in males and plays an important role in the development of the penis and testes, muscle size, bone growth, sex drive, and sperm production. Changes in serum testosterone levels at ejaculation are unclear, although the sexual function is influenced by testosterone. We measured pre- and post-ejaculatory testosterone levels over time and evaluated changes in these levels. We also measured levels of prolactin and cortisol, which are hormones that also affect sexual function. METHODS: We enrolled 7 men (age 32–41 years, mean 35.7 years) with normal sexual function, and collected blood samples before, during, and after masturbation. Testosterone, prolactin, and cortisol levels were evaluated before erection, after erection, just before ejaculation, at ejaculation, and 10 min after ejaculation. RESULTS: Serum testosterone level increased significantly over time from before erection to the moment of ejaculation, and decreased to the pre-erection level 10 min after ejaculation (pre-erection, 5.86±2.45ng/mL; at ejaculation, 7.01±3.61 ng/mL; 10 min after ejaculation, 6.22±2.89 ng/mL; p < 0.05). Cortisol increased significantly over time from before erection to after ejaculation (pre-erection, 5.63±3.82μg/dL; at ejaculation, 6.94±4.59 μg/dL; 10 min after ejaculation, 7.70±4.99 μg/dL; p < 0.05). And prolactin increased approximately 2-fold over time from before erection to after ejaculation (pre-erection, 12.83±2.36ng/mL; at ejaculation, 17.48±4.51 ng/mL; 10 min after ejaculation, 23.47±6.27 ng/mL; p < 0.05). CONCLUSIONS: All 3 hormones changed drastically with ejaculation. The increase in testosterone level may be due to prostate contraction and testicular secretion. In addition, prolactin and cortisol levels changed before and after ejaculation. Changes in hormone secretion due to ejaculation may affect daily health and sexual function. Source of Funding: None. © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e1178-e1178 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Yoshitomo Kobori* More articles by this author Akiyoshi Osaka More articles by this author Hisamitsu Ide More articles by this author Hiroshi Okada More articles by this author Gaku Arai More articles by this author Tadahiko Tokumoto More articles by this author Kiyoshi Setoguchi More articles by this author Yoji Hyodo More articles by this author Akinori Nakayama More articles by this author Yasuyuki Inoue More articles by this author Yuka Yasuda More articles by this author Shigehiro Soh More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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• W3022996820 title "MP78-13 SERUM TESTOSTERONE LEVEL RISES DRASTICALLY AT THE MOMENT OF EJACULATION" @default.
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