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• W3023222607 endingPage "e03915" @default.
• W3023222607 startingPage "e03915" @default.
• W3023222607 abstract "The codon usage pattern is a specific characteristic of each species; however, the codon usage of all of the genes in a genome is not uniform. Intriguingly, most viruses have codon usage patterns that are vastly different from the optimal codon usage of their hosts. How viral genes with different codon usage patterns are efficiently expressed during a viral infection is unclear. An analysis of the similarity between viral codon usage and the codon usage of the individual genes of a host genome has never been performed. In this study, we demonstrated that the codon usage of human RNA viruses is similar to that of some human genes, especially those involved in the cell cycle. This finding was substantiated by its concordance with previous reports of an upregulation at the protein level of some of these biological processes. It therefore suggests that some suboptimal viral codon usage patterns may actually be compatible with cellular translational machineries in infected conditions." @default.
• W3023222607 created "2020-05-13" @default.
• W3023222607 creator A5002198495 @default.
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• W3023222607 date "2020-05-01" @default.
• W3023222607 modified "2023-10-14" @default.
• W3023222607 title "Codon usage similarity between viral and some host genes suggests a codon-specific translational regulation" @default.
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• W3023222607 doi "https://doi.org/10.1016/j.heliyon.2020.e03915" @default.
• W3023222607 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/7205639" @default.
• W3023222607 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/32395662" @default.
• W3023222607 hasPublicationYear "2020" @default.
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