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- W3023225087 abstract "You have accessJournal of UrologyProstate Cancer: Detection & Screening III (PD38)1 Apr 2020PD38-08 MULTI-INSTITUTIONAL PROSPECTIVE VALIDATION OF THE NOVEL MICHIGAN UROLOGICAL SURGERY IMPROVEMENT COLLABORATIVE TRANSPERINEAL BIOPSY TEMPLATE Mahir Maruf*, Arvin George, John Wei, James Montie, David Miller, Richard C. Wu, Stephanie Ferrante, Ji Qi, Craig Rogers, Valal George, Brian Stork, and for the Michigan Urological Surgery Improvement Collaborative Mahir Maruf*Mahir Maruf* More articles by this author , Arvin GeorgeArvin George More articles by this author , John WeiJohn Wei More articles by this author , James MontieJames Montie More articles by this author , David MillerDavid Miller More articles by this author , Richard C. WuRichard C. Wu More articles by this author , Stephanie FerranteStephanie Ferrante More articles by this author , Ji QiJi Qi More articles by this author , Craig RogersCraig Rogers More articles by this author , Valal GeorgeValal George More articles by this author , Brian StorkBrian Stork More articles by this author , and for the Michigan Urological Surgery Improvement Collaborative More articles by this author View All Author Informationhttps://doi.org/10.1097/JU.0000000000000917.08AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract INTRODUCTION AND OBJECTIVE: Transrectal (TR) ultrasound–guided prostate biopsy has long been the gold standard for diagnosing prostate cancer, however, a transperineal (TP) approach has been noted to significantly decrease infectious complications by avoiding seeding theprostate with rectal flora. Prior evaluation of the modified Barzell 12-core TP template demonstrated a lower overall and ≥GG2 cancer detection rate (CDR). We aim to evaluate the novel Michigan Urological Surgery Improvement Collaborative (MUSIC) TP template. METHODS: The MUSIC TP template was developed using corelocation specific CDR data based on initial results of the Barzell template (Figure 1). All patients undergoing in-office TP or TR biopsy under local anesthesia from February to August 2019 were included for this study. Patient characteristics, CDR, and 30-day complications were prospectively collected and analyzed. A multivariable logistic regression was used to compare cancer detection rate between the two biopsy approaches, adjusting for age, prostate specific antigen (PSA), gland volume, prior cancer diagnosis, digital rectal exam (DRE), race and family history. RESULTS: In total, 5161 patients (215 TP and 4946 TR) were evaluated. The overall CDR was 53.0% for TP and 55.3% for TR (p=0.51). The rate of ≥GG2 cancer was 33.5% for TP and 38.0% for TR (p=0.18). Patients undergoing TP were more likely to be African American and with family history, and less likely to have a positive DRE result (p<0.05 each). Age at biopsy, pre-biopsy PSA, prostate volume and prior cancer diagnosis were not significantly different between the groups. On multivariable analysis, there was no significant difference in the odds of detecting any cancer (OR 0.93, p=0.64) or ≥GG2 cancer(OR 0.89, p=0.47) for TP compared to TR. While not statistically significant, the rates of infectious hospitalization were lower in those undergoing TP than TR (0.17%vs 0.71%, p=0.20). CONCLUSIONS: The new MUSIC TP biopsy template achieves similar overall and ≥GG2 CDR when compared to TRUS biopsy. TP biopsies are associated with lower rates of infectious complications. Source of Funding: BlueCross Blue Shield of Michigan © 2020 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 203Issue Supplement 4April 2020Page: e804-e804 Advertisement Copyright & Permissions© 2020 by American Urological Association Education and Research, Inc.MetricsAuthor Information Mahir Maruf* More articles by this author Arvin George More articles by this author John Wei More articles by this author James Montie More articles by this author David Miller More articles by this author Richard C. Wu More articles by this author Stephanie Ferrante More articles by this author Ji Qi More articles by this author Craig Rogers More articles by this author Valal George More articles by this author Brian Stork More articles by this author for the Michigan Urological Surgery Improvement Collaborative More articles by this author Expand All Advertisement PDF downloadLoading ..." @default.
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- W3023225087 title "PD38-08 MULTI-INSTITUTIONAL PROSPECTIVE VALIDATION OF THE NOVEL MICHIGAN UROLOGICAL SURGERY IMPROVEMENT COLLABORATIVE TRANSPERINEAL BIOPSY TEMPLATE" @default.
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