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• W3023233618 endingPage "1612" @default.
• W3023233618 startingPage "1573" @default.
• W3023233618 abstract "Ulcerative colitis (UC) is one of two major forms of inflammatory bowel disease (IBD) and as such is an important type of abnormality of mucosal immune function. Studies designed to gain increased insight into the cause of this disease are important not only because of the promise they hold for improved treatment of patients but also because of their potential to provide a deeper understanding of the mucosal immune response. In this chapter we provide a discussion of several major factors bearing on the development of UC, including its major clinical manifestations, its genetic underpinning, its relation to the gut microbiome, its association with epithelial cell abnormalities, and its immunopathogenesis. This discussion makes it apparent that UC differs from its counterpart gut inflammation, Crohn disease (CD), by the fact that it is a more superficial bowel inflammation centered on epithelial cell damage rather than bowel wall granulomatous cellular infiltration; in addition, its hallmark immune abnormality, a Th2-like interleukin-13 response by natural killer T cells is vastly different from the Th1/Th17 response characteristic of CD and is more clearly the result of a primary epithelial cell abnormality. Thus, whereas the two major forms of IBD may be driven by abnormal responses to elements of the gut microbiome, the type of abnormal response in these diseases is distinct." @default.
• W3023233618 created "2020-05-13" @default.
• W3023233618 creator A5053370481 @default.
• W3023233618 creator A5056842523 @default.
• W3023233618 date "2015-01-01" @default.
• W3023233618 modified "2023-09-27" @default.
• W3023233618 title "Ulcerative Colitis" @default.
• W3023233618 cites W1504633841 @default.
• W3023233618 cites W1511973800 @default.
• W3023233618 cites W1520365933 @default.
• W3023233618 cites W1528623386 @default.
• W3023233618 cites W1530175514 @default.
• W3023233618 cites W1558646058 @default.
• W3023233618 cites W1568944851 @default.
• W3023233618 cites W1581965845 @default.
• W3023233618 cites W1642457845 @default.
• W3023233618 cites W1670573097 @default.
• W3023233618 cites W1685245094 @default.
• W3023233618 cites W1775935655 @default.
• W3023233618 cites W1834954945 @default.
• W3023233618 cites W1904655665 @default.
• W3023233618 cites W1905191652 @default.
• W3023233618 cites W1906286317 @default.
• W3023233618 cites W1928414651 @default.
• W3023233618 cites W1935658997 @default.
• W3023233618 cites W1946093640 @default.
• W3023233618 cites W1963584531 @default.
• W3023233618 cites W1964549111 @default.
• W3023233618 cites W1965027165 @default.
• W3023233618 cites W1966159303 @default.
• W3023233618 cites W1967217097 @default.
• W3023233618 cites W1968154981 @default.
• W3023233618 cites W1968397341 @default.
• W3023233618 cites W1968909507 @default.
• W3023233618 cites W1969127506 @default.
• W3023233618 cites W1969448383 @default.
• W3023233618 cites W1969550033 @default.
• W3023233618 cites W1969842850 @default.
• W3023233618 cites W1970196341 @default.
• W3023233618 cites W1972085567 @default.
• W3023233618 cites W1972505691 @default.
• W3023233618 cites W1973024773 @default.
• W3023233618 cites W1974690724 @default.
• W3023233618 cites W1975348681 @default.
• W3023233618 cites W1975523050 @default.
• W3023233618 cites W1975969474 @default.
• W3023233618 cites W1976056371 @default.
• W3023233618 cites W1976302032 @default.
• W3023233618 cites W1977074645 @default.
• W3023233618 cites W1977235697 @default.
• W3023233618 cites W1977947961 @default.
• W3023233618 cites W1978029533 @default.
• W3023233618 cites W1978195655 @default.
• W3023233618 cites W1979013444 @default.
• W3023233618 cites W1979891329 @default.
• W3023233618 cites W1980725116 @default.
• W3023233618 cites W1981714996 @default.
• W3023233618 cites W1981904875 @default.
• W3023233618 cites W1983251816 @default.
• W3023233618 cites W1983312277 @default.
• W3023233618 cites W1984484510 @default.
• W3023233618 cites W1986991051 @default.
• W3023233618 cites W1990296143 @default.
• W3023233618 cites W1990417003 @default.
• W3023233618 cites W1990701314 @default.
• W3023233618 cites W1991136479 @default.
• W3023233618 cites W1991886741 @default.
• W3023233618 cites W1993563063 @default.
• W3023233618 cites W1993649794 @default.
• W3023233618 cites W1993688639 @default.
• W3023233618 cites W1994930629 @default.
• W3023233618 cites W1995073019 @default.
• W3023233618 cites W1996487363 @default.
• W3023233618 cites W1996759553 @default.
• W3023233618 cites W1997090182 @default.
• W3023233618 cites W1997848360 @default.
• W3023233618 cites W1998966952 @default.
• W3023233618 cites W1999523285 @default.
• W3023233618 cites W2000293606 @default.
• W3023233618 cites W2001829069 @default.
• W3023233618 cites W2003115027 @default.
• W3023233618 cites W2003521373 @default.
• W3023233618 cites W2004454505 @default.
• W3023233618 cites W2004538946 @default.
• W3023233618 cites W2004895532 @default.
• W3023233618 cites W2005311074 @default.
• W3023233618 cites W2005687210 @default.
• W3023233618 cites W2005879027 @default.
• W3023233618 cites W2006638326 @default.
• W3023233618 cites W2006741811 @default.
• W3023233618 cites W2006773330 @default.
• W3023233618 cites W2008293760 @default.
• W3023233618 cites W2008512592 @default.
• W3023233618 cites W2008717984 @default.
• W3023233618 cites W2009109388 @default.
• W3023233618 cites W2009292906 @default.
• W3023233618 cites W2009706335 @default.
• W3023233618 cites W2009938323 @default.

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